期刊
ACS COMBINATORIAL SCIENCE
卷 16, 期 5, 页码 238-243出版社
AMER CHEMICAL SOC
DOI: 10.1021/co4001524
关键词
benzo[b][1,8]naphthyridine; three-component reaction; L-proline
资金
- Major Basic Research Project of the Natural Science Foundation of the Jiangsu Higher Education Institutions [10KJA150049]
- Project of the Natural Science Foundation of Jiangsu Province [BK20131160]
- Priority Academic Project Development of Jiangsu Higher Education Institutions
- Foundation of Key Laboratory of Organic Synthesis of Jiangsu Province [JSK1210]
A facile and efficient one-pot procedure for the preparation of functionalized benzo[b][1,8]naphthyridine derivatives by three-component reaction of 2-chloroquinoline-3-carbaldehyde, 1,3-dicarbonyl compounds, and enaminones catalyzed by L-proline is described. This new protocol has the advantages of environmental friendliness, good yields, and convenient operation.
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