Copper-Catalyzed Multicomponent Coupling/Cycloisomerization Reaction between Substituted 1-Formyl-9H-β-carbolines, Secondary Amines, and Substituted Alkynes for the Synthesis of Substituted 3-Aminoindolizino[8,7-b]indoles

A copper-catalyzed efficient one step three component strategy for preparing a library of aminoindolizino[8,7-b]indoles from N-substituted 1-formyl-9H-beta-carbolines, secondary amines, and substituted alkynes with high atom economy has been developed.