期刊
ACS CATALYSIS
卷 8, 期 10, 页码 9463-9470出版社
AMER CHEMICAL SOC
DOI: 10.1021/acscatal.8b02560
关键词
manganese catalysis; condition control; indole; C-H activation; enyne
资金
- NSFC [21525208, 21472186]
- Henan Normal University [5101034011009, qd16111]
Manganese(I)-catalyzed C-H activation of indoles and divergent annulative coupling with alkyne-tethered cyclohexadienones has been realized under operationally simple conditions. These annulation systems are under condition control. The coupling in the presence of BPh3 additive followed a C-H activation-alkyne insertion-Michael addition pathway, affording an exocyclic olefin attached to a tetrahydrofuran ring. In contrast, when Zn(OAc)(2)/PivOH additives were introduced, initial olefination en route to intramolecular Diels-Alder reaction and subsequent elimination of an alcohol was followed to deliver a fused six-membered ring. The selectivity stands in contrast to those reported using rhodium(III) and cobalt(III) catalysts, highlighting the unique reactivity and selectivity of manganese catalysts.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据