期刊
ACS MEDICINAL CHEMISTRY LETTERS
卷 4, 期 12, 页码 1126-1128出版社
AMER CHEMICAL SOC
DOI: 10.1021/ml4004414
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资金
- NIAID NIH HHS [R01 AI105106] Funding Source: Medline
The search for antimalarial remedies predates modern medicine and the concept of small molecule chemotherapy, yet has played a central role in the development of both. This history is reviewed in the context of the current renaissance in antimalarial drug discovery, which is seeing modern drug discovery approaches applied to the problem for the first time: Great strides have been made in the past decade, but further innovations from the drug discovery community will be required if the ultimate dream of eradication is to be achieved.
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