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Simon Read et al.
JOURNAL OF IMMUNOLOGY (2006)
Innate immunity in multiple sclerosis: Myeloid dendritic cells in secondary progressive multiple sclerosis are activated and drive a proinflammatory immune response
Arnon Karni et al.
JOURNAL OF IMMUNOLOGY (2006)
Microglia, major player in the brain inflammation: their roles in the pathogenesis of Parkinson's disease
Yoon Seong Kim et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2006)
The roles for cytokines in the generation and maintenance of regulatory T cells
Yisong Y. Wan et al.
IMMUNOLOGICAL REVIEWS (2006)
FOXP3 controls regulatory T cell function through cooperation with NFAT
Yongqing Wu et al.
CELL (2006)
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells
Weihong Liu et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells
Nabila Seddiki et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
Circulating dendritic cells subsets and regulatory T-cells at multiple sclerosis relapse:: Differential short-term changes on corticosteroids therapy
Joaquin Navarro et al.
JOURNAL OF NEUROIMMUNOLOGY (2006)
Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) associated with pemphigoid nodularis: A case report and review of the literature
Jamie L. McGinness et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2006)
Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development (vol 103, pg 6659, 2006)
MA Gavin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX): report of the first prenatal mutation testing
L. Perroni et al.
PRENATAL DIAGNOSIS (2006)
CTLA-4 engagement and regulatory CD4+ CD25+ T cells independently control CD8+-mediated responses under costimulation blockade
Jeroen J. A. Coenen et al.
JOURNAL OF IMMUNOLOGY (2006)
Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development
MA Gavin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Anti-miRNA oligonucleotides (AMOs): ammunition to target miRNAs implicated in human disease?
J Weiler et al.
GENE THERAPY (2006)
CD25 regulatory T cells determine secondary but not primary remission in EAE:: Impact on long-term disease progression
D Gärtner et al.
JOURNAL OF NEUROIMMUNOLOGY (2006)
Vasoactive intestinal peptide induces regulatory T cells during experimental autoimmune encephalomyelitis
A Fernandez-Martin et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2006)
Microglial senescence: does the brain's immune system have an expiration date?
Wolfgang J. Streit
TRENDS IN NEUROSCIENCES (2006)
Reduced suppressive effect of CD4+CD25high regulatory T cells on the T cell immune response against myelin oligodendrocyte glycoprotein in patients with multiple sclerosis
J Haas et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2005)
TLR signaling tailors innate immune responses in human microglia and astrocytes
CS Jack et al.
JOURNAL OF IMMUNOLOGY (2005)
Natural recovery and protection from autoimmune encephalomyelitis:: Contribution of CD4+CD25+ regulatory cells within the central nervous system
MJ McGeachy et al.
JOURNAL OF IMMUNOLOGY (2005)
Decreased FOXP3 levels in multiple sclerosis patients
J Huan et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2005)
Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single-cell level
G Roncador et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2005)
The number of human peripheral blood CD4+ CD25high regulatory T cells increases with age
R Gregg et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2005)
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
A Nimmerjahn et al.
SCIENCE (2005)
TGF-β1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells
JC Marie et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Microglial cell population dynamics in the injured adult central nervous system
R Ladeby et al.
BRAIN RESEARCH REVIEWS (2005)
T cells that cannot respond to TGF-β escape control by CD4+CD25+ regulatory T cells
L Fahlén et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis
EJ McMahon et al.
NATURE MEDICINE (2005)
Cutting edge:: Contact-mediated suppression by CD4+-CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism
DC Gondek et al.
JOURNAL OF IMMUNOLOGY (2005)
Congruent effects of estrogen and T-cell receptor peptide therapy on regulatory T cells in EAE and MS
H Offner et al.
INTERNATIONAL REVIEWS OF IMMUNOLOGY (2005)
Microglia as potential contributors to motor neuron injury in amyotrophic lateral sclerosis
SA Sargsyan et al.
GLIA (2005)
Blood-derived dendritic cells in an acute brain injury
TA Newman et al.
JOURNAL OF NEUROIMMUNOLOGY (2005)
Cutting edge:: TGF-β induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7
MC Fantini et al.
JOURNAL OF IMMUNOLOGY (2004)
Cutting edge:: Human CD4+CD25+ T cells restrain the maturation and antigen-presenting function of dendritic cells
N Misra et al.
JOURNAL OF IMMUNOLOGY (2004)
Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis
V Viglietta et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
TGF-β regulates in vivo expansion of Foxp3-expressing CD4+CD25+ regulatory T cells responsible for protection against diabetes
YF Peng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
GITR, a member of the TNF receptor superfamily, is costimulatory to mouse T lymphocyte subpopulations
S Ronchetti et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2004)
IL-10 is involved in the suppression of experimental autoimmune encephalomyelitis by CD25+CD4+ regulatory T cells
XM Zhang et al.
INTERNATIONAL IMMUNOLOGY (2004)
Activation requirements for the induction of CD4+CD25+ T cell suppressor function
AM Thornton et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2004)
Mycobacteria and other environmental organisms as immunomodulators for immunoregulatory disorders
GAW Rook et al.
SPRINGER SEMINARS IN IMMUNOPATHOLOGY (2004)
Human T regulatory cells can use the perforin pathway to cause autologous target cell death
WJ Grossman et al.
IMMUNITY (2004)
Constitutive and cytokine-induced GITR ligand expression on human retinal pigment epithelium and photoreceptors
BJ Kim et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2004)
Interleukin-2 is essential for CD4+CD25+ regulatory T cell function
M de la Rosa et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2004)
Prospective immunological profiling in a case of immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX)
AC Bakke et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2004)
Dopamine, through the extracellular signal-regulated kinase pathway, downregulates CD4+CD25+ regulatory T-cell activity:: Implications for neurodegeneration
J Kipnis et al.
JOURNAL OF NEUROSCIENCE (2004)
Microglia and Alzheimer's disease pathogenesis
WJ Streit
JOURNAL OF NEUROSCIENCE RESEARCH (2004)
Vaccination with autoantigen protects against aggregated β-amyloid and glutamate toxicity by controlling microglia:: effect of CD4+CD25+ T cells
H Avidan et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2004)
Cutting edge:: TGF-β signaling is required for the in vivo expansion and immunosuppressive capacity of regulatory CD4+ CD25+ T cells
S Huber et al.
JOURNAL OF IMMUNOLOGY (2004)
CD28 disruption exacerbates inflammation in Tgf-β1-/- mice:: in vivo suppression by CD4+CD25+ regulatory T cells independent of autocrine TGF-β1
M Mamura et al.
BLOOD (2004)
Decreased CD14+ CCR2+ monocytes in active multiple sclerosis
H Nakajima et al.
NEUROSCIENCE LETTERS (2004)
Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells
H Yagi et al.
INTERNATIONAL IMMUNOLOGY (2004)
Cutting edge:: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function
AM Thornton et al.
JOURNAL OF IMMUNOLOGY (2004)
The intermediate filament GFAP is important for the control of experimental murine Staphylococcus aureus-induced brain abscess and Toxoplasma encephalitis
W Stenzel et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2004)
Naturally arising CD4(+) regulatory T cells for immunologic self-tolerance and negative control of immune responses
S Sakaguchi
ANNUAL REVIEW OF IMMUNOLOGY (2004)
VIP/PACAP oppositely affects immature and mature dendritic cell expression of CD80/CD86 and the stimulatory activity for CD4+ T cells
M Delgado et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2004)
Dual effect of CD4+CD25+ regulatory T cells in neurodegeneration:: A dialogue with microglia
J Kipnis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Clearance of apoptotic cells: Getting rid of the corpses
K Lauber et al.
MOLECULAR CELL (2004)
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-β induction of transcription factor Foxp3
WJ Chen et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Loss of tolerance and autoimmunity affecting multiple organs in STAT5A/5B-deficient mice1
JW Snow et al.
JOURNAL OF IMMUNOLOGY (2003)
Thymic export function and T cell homeostasis in patients with relapsing remitting multiple sclerosis
A Hug et al.
JOURNAL OF IMMUNOLOGY (2003)
Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis
E Gambineri et al.
CURRENT OPINION IN RHEUMATOLOGY (2003)
Expression of brain-derived neurotrophic factor (BDNF) and inducible nitric oxide synthase (iNOS) in rat astrocyte cultures treated with Levetiracetam
V Cardile et al.
BRAIN RESEARCH (2003)
An essential role for Scurfin in CD4+CD25+ T regulatory cells
R Khattri et al.
NATURE IMMUNOLOGY (2003)
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
JD Fontenot et al.
NATURE IMMUNOLOGY (2003)
Impairment of TGF-β signaling in T cells increases susceptibility to experimental autoimmune hepatitis in mice
C Schramm et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2003)
Control of regulatory T cell development by the transcription factor Foxp3
S Hori et al.
SCIENCE (2003)
The brain as an immune privileged site: dendritic cells of the central nervous system inhibit T cell activation
T Suter et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2003)
Pathway studio - the analysis and navigation of molecular networks
A Nikitin et al.
BIOINFORMATICS (2003)
Granulomas in schistosome and mycobacterial infections: a model of local immune responses
M Sandor et al.
TRENDS IN IMMUNOLOGY (2003)
CD40 ligation releases immature dendritic cells from the control of regulatory CD4(+)CD25(+) T cells
P Serra et al.
IMMUNITY (2003)
Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit the production of inflammatory mediators by activated microglia
M Delgado et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2003)
Broad expression of Toll-like receptors in the human central nervous system
M Bsibsi et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2002)
Cutting edge:: CD4+CD25+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis
AP Kohm et al.
JOURNAL OF IMMUNOLOGY (2002)
Homeostasis of peripheral CD4+ T cells:: IL-2Rα and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers
ARM Almeida et al.
JOURNAL OF IMMUNOLOGY (2002)
Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide promote in vivo generation of memory Th2 cells
M Delgado et al.
FASEB JOURNAL (2002)
CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rβ-deficient mice:: implications for the nonredundant function of IL-2
TR Malek et al.
IMMUNITY (2002)
Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit chemokine production in activated microglia
M Delgado et al.
GLIA (2002)
Stimulation of CD25+CD4+regulatory T cells through GITR breaks immunological self-tolerance
J Shimizu et al.
NATURE IMMUNOLOGY (2002)
CD4+CD25+ immunoregulatory T cells:: Gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor
RS McHugh et al.
IMMUNITY (2002)
Elevated expression of CCR5 by myeloid (CD11c(+)) blood dendritic cells in multiple sclerosis and acute optic neuritis
M Pashenkov et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2002)
Novel mutations of FOXP3 in two Japanese patients with immune dysregulation, polyendocrinopathy, enteropathy, X linked syndrome (IPEX)
I Kobayashi et al.
JOURNAL OF MEDICAL GENETICS (2001)
CCR1+/CCR5+mononuclear phagocytes accumulate in the central nervous system of patients with multiple sclerosis
C Trebst et al.
AMERICAN JOURNAL OF PATHOLOGY (2001)
A long-term survivor with the immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome.
I Kobayashi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2001)
Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4+CD25+ regulatory T cells
A Iellem et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2001)
CD4+CD25high regulatory cells in human peripheral blood
C Baecher-Allan et al.
JOURNAL OF IMMUNOLOGY (2001)
Microglia and Prion disease
DR Brown
MICROSCOPY RESEARCH AND TECHNIQUE (2001)
Treatment of the immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) by allogeneic bone marrow transplantation
O Baud et al.
NEW ENGLAND JOURNAL OF MEDICINE (2001)
Expression of inducible nitric oxide synthase and nitrotyrosine in multiple sclerosis lesions
JSH Liu et al.
AMERICAN JOURNAL OF PATHOLOGY (2001)
Developmental plasticity of CNS microglia
L Santambrogio et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Differential cellular accumulation of connective tissue growth factor defines a subset of reactive astrocytes, invading fibroblasts, and endothelial cells following central nervous system injury in rats and humans
JM Schwab et al.
JOURNAL OF NEUROTRAUMA (2001)
Neonatal diabetes mellitus, enteropathy, thrombocytopenia, and endocrinopathy: Further evidence for an X-linked lethal syndrome
E Levy-Labad et al.
JOURNAL OF PEDIATRICS (2001)
Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis
DR Huang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2001)
Brain dendritic cells and macrophages/microglia in central nervous system inflammation
HG Fischer et al.
JOURNAL OF IMMUNOLOGY (2001)
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
RS Wildin et al.
NATURE GENETICS (2001)
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
ME Brunkow et al.
NATURE GENETICS (2001)
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
CL Bennett et al.
NATURE GENETICS (2001)
Nerve-driven immunity: Neuropeptides regulate cytokine secretion of T cells and intestinal epithelial cells in a direct, powerful and contextual manner
M Levite et al.
ANNALS OF ONCOLOGY (2001)
Neuropeptide Y cotransmission with norepinephrine in the sympathetic nerve-macrophage interplay
RH Straub et al.
JOURNAL OF NEUROCHEMISTRY (2000)
Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2
L Izikson et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25+CD4+ regulatory cells that control intestinal inflammation
S Read et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
CCR5 Δ32, matrix metalloproteinase-9 and disease activity in multiple sclerosis
F Sellebjerg et al.
JOURNAL OF NEUROIMMUNOLOGY (2000)
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