4.1 Review

Biology and treatment of the 5q-syndrome

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A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q-syndrome

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Identification of miR-145 and miR-146a as mediators of the 5q-syndrome phenotype

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A critical role for phosphatase haplodeficiency in the selective suppression of deletion 5q MDS by lenalidomide

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Identification of RPS14 as a 5q- syndrome gene by RNA interference screen

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An erythroid differentiation signature predicts response to lenalidomide in myelodysplastic syndrome

Benjamin L. Ebert et al.

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Gene expression profiling of CD34+ cells in patients with the 5q-syndrome

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Lenalidomide inhibits the malignant clone and up-regulates the SPARC gene mapping to the commonly deleted region in 5q-syndrome patients

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Lenalidomide in the myelodysplastic syndrome with chromosome 5q deletion

Alan List et al.

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Protein phosphatase 2A stabilizes human securin, whose phosphorylated forms are degraded via the SCF ubiquitin ligase

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Efficacy of lenalidomide in myelodysplastic syndromes

A List et al.

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The Treacher!Collins syndrome (TCOF1) gene product is involved in ribosomal DNA gene transcription by interacting with upstream binding factor

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Mutations in SBDS are associated with Shwachman-Diamond syndrome

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Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase

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Structure of the dimerization and beta-catenin-binding region of alpha-catenin

S Pokutta et al.

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