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注意：仅列出部分参考文献，下载原文获取全部文献信息。Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet
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BLOOD (2010)
Comparable survival after HLA-well-matched unrelated or matched sibling donor transplantation for acute myeloid leukemia in first remission with unfavorable cytogenetics at diagnosis
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BLOOD (2010)
Zosuquidar, a novel modulator of P-glycoprotein, does not improve the outcome of older patients with newly diagnosed acute myeloid leukemia: a randomized, placebo-controlled trial of the Eastern Cooperative Oncology Group 3999
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A novel prognostic model in elderly patients with acute myeloid leukemia: results of 909 patients entered into the prospective AML96 trial
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BLOOD (2010)
Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials
David Grimwade et al.
BLOOD (2010)
Clinical, Molecular, and Prognostic Significance of WHO Type inv(3)(q21q26.2)/t(3;3)(q21;q26.2) and Various Other 3q Abnormalities in Acute Myeloid Leukemia
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JOURNAL OF CLINICAL ONCOLOGY (2010)
Single-Agent Laromustine, A Novel Alkylating Agent, Has Significant Activity in Older Patients With Previously Untreated Poor-Risk Acute Myeloid Leukemia
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JOURNAL OF CLINICAL ONCOLOGY (2010)
High EVI1 Expression Predicts Outcome in Younger Adult Patients With Acute Myeloid Leukemia and Is Associated With Distinct Cytogenetic Abnormalities
Stefan Groeschel et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
Phase II Study of Clofarabine Monotherapy in Previously Untreated Older Adults With Acute Myeloid Leukemia and Unfavorable Prognostic Factors
Hagop M. Kantarjian et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
European Development of Clofarabine as Treatment for Older Patients With Acute Myeloid Leukemia Considered Unsuitable for Intensive Chemotherapy
Alan K. Burnett et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
Prospective Evaluation of Allogeneic Hematopoietic Stem-Cell Transplantation From Matched Related and Matched Unrelated Donors in Younger Adults With High-Risk Acute Myeloid Leukemia: German-Austrian Trial AMLHD98A
Richard F. Schlenk et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
Complete remission and early death after intensive chemotherapy in patients aged 60 years or older with acute myeloid leukaemia: a web-based application for prediction of outcomes
Utz Krug et al.
LANCET (2010)
Immunophenotypic features of acute myeloid leukemia with inv(3)(q21q26.2)/t(3;3)(q21;q26.2)
Bruno C. Medeiros et al.
LEUKEMIA RESEARCH (2010)
Time from diagnosis to treatment initiation predicts survival in younger, but not older, acute myeloid leukemia patients
Mikkael A. Sekeres et al.
BLOOD (2009)
Prognostic factor analysis of the survival of elderly patients with AML in the MRC AML11 and LRF AML14 trials
Keith Wheatley et al.
BRITISH JOURNAL OF HAEMATOLOGY (2009)
Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia in First Complete Remission Systematic Review and Meta-analysis of Prospective Clinical Trials
John Koreth et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2009)
The prognostic impact of 17p (p53) deletion in 2272 adults with acute myeloid leukemia
H. Seifert et al.
LEUKEMIA (2009)
5q-myelodysplastic syndromes: chromosome 5q genes direct a tumor-suppression network sensing actin dynamics
K. M. Eisenmann et al.
ONCOGENE (2009)
Mutated and non-mutated TP53 as targets in the treatment of leukaemia
H. Nahi et al.
BRITISH JOURNAL OF HAEMATOLOGY (2008)
Identification of a novel and myeloid specific role of the leukemia-associated fusion protein DEK-NUP214 leading to increased protein synthesis
Malin Ageberg et al.
GENES CHROMOSOMES & CANCER (2008)
Monosomal karyotype in acute myeloid leukemia:: A better indicator of poor prognosis than a complex karyotype
Dimitri A. Breems et al.
JOURNAL OF CLINICAL ONCOLOGY (2008)
Genetics of therapy-related myelodysplasia and acute myeloid leukemia
J. Pedersen-Bjergaard et al.
LEUKEMIA (2008)
Chromosomal aberrations in 17p predict in vitro drug resistance and short overall survival in acute myeloid leukemia
Hareth Nahi et al.
LEUKEMIA & LYMPHOMA (2008)
Identification of RPS14 as a 5q- syndrome gene by RNA interference screen
Benjamin L. Ebert et al.
NATURE (2008)
Cytogenetic, molecular genetic, and clinical characteristics of acute myeloid leukemia with a complex karyotype
Krzysztof Mrozek
SEMINARS IN ONCOLOGY (2008)
Myeloproliferative defects following targeting of the Drf1 gene encoding the mammalian diaphanous-related formin mDia1
Jun Peng et al.
CANCER RESEARCH (2007)
High expression levels of the ETS-related gene, ERG, predict adverse outcome and improve molecular risk-based classification of cytogenetically normal acute myeloid leukemia:: A Cancer and Leukemia Group B study
Guido Marcucci et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
A phase III randomized trial of intensive induction and consolidation chemotherapy ± oblimersen, a pro-apoptotic Bcl-2 antisense oligonucleotide in untreated acute myeloid leukemia patients >60 years old
G. Marcucci et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
Philadelphia chromosome-positive acute myeloid leukemia - A rare aggressive leukemia with clinicopathologic features distinct from chronic myeloid leukemia in myeloid blast crisis
Chad P. Soupir et al.
AMERICAN JOURNAL OF CLINICAL PATHOLOGY (2007)
Chromosome 5q deletion and epigenetic suppression of the gene encoding alpha-catenin (CTNNA1) in myeloid cell transformation
Ting Xi Liu et al.
NATURE MEDICINE (2007)
Various distinctive cytogenetic abnormalities in patients with acute myeloid leukaemia aged 60 years and older express adverse prognostic value: results from a prospective clinical trial
Bronno van der Holt et al.
BRITISH JOURNAL OF HAEMATOLOGY (2007)
Blood and marrow transplantation in elderly acute myeloid leukaemia patients - older certainly is not better
T. L. Kiss et al.
BONE MARROW TRANSPLANTATION (2007)
Cytogenetics and age are major determinants of outcome in intensively treated acute myeloid leukemia patients older than 60 years:: Results from AMLSG trial AML HD98-B
Stefan Froehling et al.
BLOOD (2006)
GAB2 is a novel target of 11q amplification in AML/MDS
Andrea Zatkova et al.
GENES CHROMOSOMES & CANCER (2006)
Disclosure of candidate genes in acute myeloid leukemia with complex karyotypes using microarray-based molecular characterization
Frank G. Ruecker et al.
JOURNAL OF CLINICAL ONCOLOGY (2006)
A retrospective study of 69 patients with t(6;9)(p23;q34) AML emphasizes the need for a prospective, multicenter initiative for rare 'poor prognosis' myeloid malignancies
M. L. Slovak et al.
LEUKEMIA (2006)
Pretreatment cytogenetics add to other prognostic factors predicting complete remission and long-term outcome in patients 60 years of age or older with acute myeloid leukemia:: results from Cancer and Leukemia Group B 8461
Sherif S. Farag et al.
BLOOD (2006)
MYC-containing double minutes in hematologic malignancies:: evidence in favor of the episome model and exclusion of MYC as the target gene
CT Storlazzi et al.
HUMAN MOLECULAR GENETICS (2006)
PRIMA-1 induces apoptosis in acute myeloid leukaemia cells with p53 gene deletion
H Nahi et al.
BRITISH JOURNAL OF HAEMATOLOGY (2006)
Overexpression of the ETS-related gene, ERG, predicts a worse outcome in acute myeloid leukemia with normal karyotype:: A cancer and leukemia group B study
G Marcucci et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Comparative outcome of reduced intensity and myeloablative conditioning regimen in HLA identical sibling allogeneic haematopoietic stem cell transplantation for patients older than 50 years of age with acute myeloblastic leukaemia: a retrospective survey from the Acute Leukemia Working Party (ALWP) of the European group for Blood and Marrow Transplantation (EBMT)
M Aoudjhane et al.
LEUKEMIA (2005)
Acute myeloid leukemia with a complex aberrant karyotype is a distinct biological entity characterized by genomic imbalances and a specific gene expression profile
C Schoch et al.
GENES CHROMOSOMES & CANCER (2005)
Efficacy of allogeneic hematopoietic stem cell transplantation depends on cytogenetic risk for acute myeloid leukemia in first disease remission - A metaanalysis
M Yanada et al.
CANCER (2005)
Acute myeloid leukemia with complex karyotypes and abnormal chromosome 21:: Amplification discloses overexpression of APP, ETS2, and ERG genes
CD Baldus et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Mutations of AML1 are common in therapy-related myelodysplasia following therapy with alkylating agents and are significantly associated with deletion or loss of chromosome arm 7q and with subsequent leukemic transformation
DH Christiansen et al.
BLOOD (2004)
Expression analyses identify MLL as a prominent target of 11q23 amplification and support an etiologic role for MLL gain of function in myeloid malignancies
B Poppe et al.
BLOOD (2004)
Somatic inactivation of Nfl in hematopoietic cells results in a progressive myeloproliferative disorder
DT Le et al.
BLOOD (2004)
Philadelphia chromosome positive myelodysplastic syndrome and acute myeloid leukemia-retrospective study and review of literature
YK Keung et al.
LEUKEMIA RESEARCH (2004)
Targeting the multidrug resistance-1 transporter in AML: molecular regulation and therapeutic strategies
D Mahadevan et al.
BLOOD (2004)
Methylation of p15INK4B is common, is associated with deletion of genes on chromosome arm 7q and predicts a poor prognosis in therapy-related myelodysplasia and acute myeloid leukemia
DH Christiansen et al.
LEUKEMIA (2003)
Aberrant p15 gene promoter methylation in therapy-related myelodysplastic syndrome and acute myeloid leukaemia:: clinicopathological and karyotypic associations
WY Au et al.
BRITISH JOURNAL OF HAEMATOLOGY (2003)
High EVI1 expression predicts poor survival in acute myeloid leukemia:: a study of 319 de novo AML patients
SBV van Doorn-Khosrovani et al.
BLOOD (2003)
Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia:: results from Cancer and Leukemia Group B (CALGB 8461)
JC Byrd et al.
BLOOD (2002)
Loss of genetic material is more common than gain in acute myeloid leukemia with complex aberrant karyotype:: A detailed analysis of 125 cases using conventional chromosome analysis and fluorescence in situ hybridization including 24-color FISH
C Schoch et al.
GENES CHROMOSOMES & CANCER (2002)
Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia:: association with FAB subtypes and identification of subgroups with poor prognosis
C Thiede et al.
BLOOD (2002)
Spectral karyotyping in patients with acute myeloid leukemia and a complex karyotype shows hidden aberrations, including recurrent overrepresentation of 21q, 11q, and 22q
K Mrózek et al.
GENES CHROMOSOMES & CANCER (2002)
Identification of cytogenetic subclasses and recurring chromosomal aberrations in AML and MDS with complex karyotypes using M-FISH
H Van Limbergen et al.
GENES CHROMOSOMES & CANCER (2002)
The predictive value of hierarchical cytogenetic classification in older adults with acute myeloid leukemia (AML): analysis of 1065 patients entered into the United Kingdom Medical Research Council AML11 trial
D Grimwade et al.
BLOOD (2001)
FLT3, RAS, and TP53 mutations in elderly patients with acute myeloid leukemia
DL Stirewalt et al.
BLOOD (2001)
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