期刊
JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH
卷 7, 期 4, 页码 437-445出版社
SPRINGER
DOI: 10.1007/s12265-014-9562-8
关键词
Critical limb ischemia; Angiosome; Drug eluting; Angiogenesis; Stemcell therapy; Gene cell therapy; Spinal cord stimulation; Intermittent pneumatic compression
Patients with critical limb ischemia (CLI) represent the highest risk patients with peripheral artery disease (PAD), with high rates of death, amputation, and other cardiovascular events. Previously, nonsurgical options for patients with CLI were limited. However, advances in endovascular techniques such as angiosome-based revascularization and technologies such as drug-eluting balloon and stent platforms have dramatically improved the therapeutic outlook. Additionally, advances in stem cell-based therapy and angiogenic factors show promise as adjuvant medical therapy.
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