期刊
JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH
卷 4, 期 5, 页码 646-654出版社
SPRINGER
DOI: 10.1007/s12265-011-9289-8
关键词
Pediatric; Cardiac patch; Scaffold; Biomaterial; Tissue engineering; Cardiac surgery; Natural polymer; Synthetic polymer
资金
- Texas Children's Hospital
- Virginia and L.E. Simmons Family Foundation
This article reviews current applications and novel candidate biomaterials for use as tissue-engineered scaffolds in pediatric cardiac tissue engineering. This overview of different types of biomaterials includes naturally derived and synthetic polymers and their biological, physical, and biomechanical properties for the use as a patch or baffle for surgical reconstruction of congenital heart defects. Applications and characteristics of composite biomaterials are highlighted with their respective feasibilities in use as cardiac scaffolds. Currently, a wide range of biomaterials has been introduced for cardiovascular reconstruction for complex congenital cardiac defects. However, there are still many remaining challenges for engineered tissue implantations.
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