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Han Du et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Suppression of B-cell lymphomagenesis by the BH3-only proteins Bmf and Bad
Anna Frenzel et al.
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Akt3-Mediated Resistance to Apoptosis in B-RAF-Targeted Melanoma Cells
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Displacement of Bim by Bmf and Puma rather than increase in Bim level mediates paclitaxel-induced apoptosis in breast cancer cells
O. Kutuk et al.
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MOLECULAR AND CELLULAR BIOLOGY (2010)
The BCL-2 Family Reunion
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Inhibition of Mutated, Activated BRAF in Metastatic Melanoma
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NEW ENGLAND JOURNAL OF MEDICINE (2010)
αB-crystallin is mutant B-RAF regulated and contributes to cyclin D1 turnover in melanocytic cells
Rong Hu et al.
PIGMENT CELL & MELANOMA RESEARCH (2010)
Apoptosis of human melanoma cells induced by inhibition of B-RAFV600E involves preferential splicing of bimS
C. C. Jiang et al.
CELL DEATH & DISEASE (2010)
Mitogen-Activated Protein Kinase Inhibition Induces Translocation of Bmf to Promote Apoptosis in Melanoma
Matthew W. VanBrocklin et al.
CANCER RESEARCH (2009)
The role of BH3-only protein Bim extends beyond inhibiting Bcl-2-like prosurvival proteins
Delphine Merino et al.
JOURNAL OF CELL BIOLOGY (2009)
Mcl-1 Is Required for Melanoma Cell Resistance to Anoikis
Karen Boisvert-Adamo et al.
MOLECULAR CANCER RESEARCH (2009)
βTrCP- and Rsk1/2-Mediated Degradation of BimEL Inhibits Apoptosis
Elinor Dehan et al.
MOLECULAR CELL (2009)
Oncogenic B-RafV600E inhibits apoptosis and promotes ERK-dependent inactivation of Bad and Bim
Clare Sheridan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Loss of the BH3-only protein Bmf impairs B cell homeostasis and accelerates γ irradiation-induced thymic lymphoma development
Verena Labi et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Mutant B-RAF mediates resistance to anoikis via Bad and Bim
K. Boisvert-Adamo et al.
ONCOGENE (2008)
Oncogenic BRAFV600E inhibits BIM expression to promote melanoma cell survival
Robert A. Cartlidge et al.
PIGMENT CELL & MELANOMA RESEARCH (2008)
Functional role and oncogene-regulated expression of the BH3-only factor Bmf in mammary epithelial anoikis and morphogenesis
Tobias Schmelzle et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Bim, Bad and Bmf: intrinsically unstructured BH3-only proteins that undergo a localized conformational change upon binding to prosurvival Bcl-2 targets
M. G. Hinds et al.
CELL DEATH AND DIFFERENTIATION (2007)
p38 MAP kinase mediates apoptosis through phosphorylation of BimEL at Ser-65
Beibei Cai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
B-RAF and PI-3 kinase signaling protect melanoma cells from anoikis
K. Boisvert-Adamo et al.
ONCOGENE (2006)
Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members
Michael Certo et al.
CANCER CELL (2006)
Structural bioinformatics-based design of selective, irreversible kinase inhibitors
MS Cohen et al.
SCIENCE (2005)
BH3 domains of BH3-only proteins differentially regulate bax-mediated mitochondrial membrane permeabilization both directly and indirectly
T Kuwana et al.
MOLECULAR CELL (2005)
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
L Chen et al.
MOLECULAR CELL (2005)
Role of Bim in the survival pathway induced by Raf in epithelial cells
M Marani et al.
ONCOGENE (2004)
Extracellular signal-regulated kinases 1/2 are serum-stimulated BimEL kinases that bind to the BH3-only protein BimEL causing its phosphorylation and turnover
R Ley et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Characterization of the c-Jun N-terminal kinase-BimEL signaling pathway in neuronal apoptosis
EBE Becker et al.
JOURNAL OF NEUROSCIENCE (2004)
Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function
F Luciano et al.
ONCOGENE (2003)
Adhesion-dependent activation of the ERK1/2 cascade is by-passed in melanoma cells
SR Conner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis
GV Putcha et al.
NEURON (2003)
Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim
R Ley et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis
K Lei et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Constitutive activation of extracellular signal-regulated kinase 2 by synergistic point mutations
MA Emrick et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Bmf: A proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis
H Puthalakath et al.
SCIENCE (2001)
BCL-2, BCL-XL sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis
EHYA Cheng et al.
MOLECULAR CELL (2001)