期刊
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY
卷 3, 期 3, 页码 -出版社
COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
DOI: 10.1101/cshperspect.a004226
关键词
-
类别
资金
- National Institutes of Health
- Fonds de la Recherche Scientifique Medicale [3.4636.04]
- European Union [LSHB-CT-2004-005137]
- Belgian Federal Science Policy Office [P6/25]
- ANR [RPV07094LSA]
- Inserm
- AP-HP
- PHC
Calcium signaling results from a complex interplay between activation and inactivation of intracellular and extracellular calcium permeable channels. This complexity is obvious from the pattern of calcium signals observed with modest, physiological concentrations of calcium-mobilizing agonists, which typically present as sequential regenerative discharges of stored calcium, a process referred to as calcium oscillations. In this review, we discuss recent advances in understanding the underlying mechanism of calcium oscillations through the power of mathematical modeling. We also summarize recent findings on the role of calcium entry through store-operated channels in sustaining calcium oscillations and in the mechanism by which calcium oscillations couple to downstream effectors.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据