期刊
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY
卷 1, 期 4, 页码 -出版社
COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
DOI: 10.1101/cshperspect.a002923
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资金
- NIH [RO1GM52112]
- UT MDACC NCI Core [CA-16672]
- Wellcome Trust
- MRC
- BBSRC
- AICR
- Fight for Sight
- Texas ARP [003657-00082006]
Cell-cell junctions continue to capture the interest of cell and developmental biologists, with an emerging area being the molecular means by which junctional signals relate to gene activity in the nucleus. Although complexities often arise in determining the direct versus indirect nature of such signal transduction, it is clear that such pathways are essential for the function of tissues and that alterationsmay contribute to many pathological outcomes. This review assesses a variety of cell-cell junction-to-nuclear signaling pathways, and outlines interesting areas for further study.
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