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Joni M. Seeling et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
The Unexpected Roles of Aurora A Kinase in Gliobastoma Recurrences
Estelle Willems et al.
TARGETED ONCOLOGY (2017)
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COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2017)
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Richard Bayliss et al.
FEBS JOURNAL (2017)
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Foong Lyn Chan et al.
NUCLEIC ACIDS RESEARCH (2017)
Aurora A Kinase Is a Priority Pharmaceutical Target for the Treatment of Cancers
Arun Prasath Damodaran et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2017)
Aurora-B kinase pathway controls the lateral to end-on conversion of kinetochore-microtubule attachments in human cells
Roshan L. Shrestha et al.
NATURE COMMUNICATIONS (2017)
Aurora kinases: novel therapy targets in cancers
Anqun Tang et al.
ONCOTARGET (2017)
Differential regulation of H3S10 phosphorylation, mitosis progression and cell fate by Aurora Kinase B and C in mouse preimplantation embryos
Wenzhi Li et al.
PROTEIN & CELL (2017)
Aurora Kinase A Is a Prognostic Marker in Colorectal Adenocarcinoma
Hyun Min Koh et al.
JOURNAL OF PATHOLOGY AND TRANSLATIONAL MEDICINE (2017)
How Do Protein Kinases Take a Selfie (Autophosphorylate)?
Jonah Beenstock et al.
TRENDS IN BIOCHEMICAL SCIENCES (2016)
AURKA promotes cell migration and invasion of head and neck squamous cell carcinoma through regulation of the AURKA/Akt/FAK signaling pathway
Jichang Wu et al.
ONCOLOGY LETTERS (2016)
Nuclear AURKA acquires kinase-independent transactivating function to enhance breast cancer stem cell phenotype
Feimeng Zheng et al.
NATURE COMMUNICATIONS (2016)
Aurora-A recruitment and centrosomal maturation are regulated by a Golgi-activated pool of Src during G2
Maria Luisa Barretta et al.
NATURE COMMUNICATIONS (2016)
Essential role of autoactivation circuitry on Aurora B-mediated H2AX-pS121 in mitosis
Midori Shimada et al.
NATURE COMMUNICATIONS (2016)
A FRET biosensor reveals spatiotemporal activation and functions of aurora kinase A in living cells
Giulia Bertolin et al.
NATURE COMMUNICATIONS (2016)
Ku70 Serine 155 mediates Aurora B inhibition and activation of the DNA damage response
Victoria L. Fell et al.
SCIENTIFIC REPORTS (2016)
Aurora B kinase controls the separation of centromeric and telomeric heterochromatin
Yannick Gachet et al.
MOLECULAR & CELLULAR ONCOLOGY (2016)
Mio depletion links mTOR regulation to Aurora A and Plk1 activation at mitotic centrosomes
Melpomeni Platani et al.
JOURNAL OF CELL BIOLOGY (2015)
Aurora B prevents chromosome arm separation defects by promoting telomere dispersion and disjunction
Celine Reyes et al.
JOURNAL OF CELL BIOLOGY (2015)
Aurora kinase B inhibition reduces the proliferation of metastatic melanoma cells and enhances the response to chemotherapy
Letizia Porcelli et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2015)
Aurora B Overexpression Causes Aneuploidy and p21Cip1 Repression during Tumor Development
Alejandra Gonzalez-Loyola et al.
MOLECULAR AND CELLULAR BIOLOGY (2015)
Aurora Kinase B Regulates Telomerase Activity via a Centromeric RNA in Stem Cells
Jan-Philipp Mallm et al.
CELL REPORTS (2015)
Inter-domain Cooperation in INCENP Promotes Aurora B Relocation from Centromeres to Microtubules
Armando van der Horst et al.
CELL REPORTS (2015)
Glioblastoma stem-like cells: at the root of tumor recurrence and a therapeutic target
Melanie Jackson et al.
CARCINOGENESIS (2015)
Functions of Aurora kinase C in meiosis and cancer
Suzanne M. Quartuccio et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2015)
Aurora A is a prognostic marker for breast cancer arising in BRCA2 mutation carriers
Margret Aradottir et al.
JOURNAL OF PATHOLOGY CLINICAL RESEARCH (2015)
The role of mitotic kinases in coupling the centrosome cycle with the assembly of the mitotic spindle
Gang Wang et al.
JOURNAL OF CELL SCIENCE (2014)
The mitotic kinase Aurora-A promotes distant metastases by inducing epithelial-to-mesenchymal transition in ERα+ breast cancer cells
A. B. D'Assoro et al.
ONCOGENE (2014)
Molecular mechanism of Aurora A kinase autophosphorylation and its allosteric activation by TPX2
Adelajda Zorba et al.
ELIFE (2014)
Overexpression of Rap-1A Indicates a Poor Prognosis for Oral Cavity Squamous Cell Carcinoma and Promotes Tumor Cell Invasion via Aurora-A Modulation
Chang-Han Chen et al.
AMERICAN JOURNAL OF PATHOLOGY (2013)
Chromosome Instability Modulated by BMI1-AURKA Signaling Drives Progression in Head and Neck Cancer
Chun-Hung Chou et al.
CANCER RESEARCH (2013)
Aurora A kinase and its substrate TACC3 are required for central spindle assembly
Antonios Lioutas et al.
EMBO REPORTS (2013)
Aurora A is involved in central spindle assembly through phosphorylation of Ser 19 in P150Glued
David Reboutier et al.
JOURNAL OF CELL BIOLOGY (2013)
Aurora at the pole and equator: overlapping functions of Aurora kinases in the mitotic spindle
Helfrid Hochegger et al.
OPEN BIOLOGY (2013)
Ubiquitination site preferences in anaphase promoting complex/cyclosome (APC/C) substrates
Mingwei Min et al.
OPEN BIOLOGY (2013)
p53 negatively regulates Aurora A via both transcriptional and posttranslational regulation
Chun-Chi Wu et al.
CELL CYCLE (2012)
Regulation of Embryonic and Induced Pluripotency by Aurora Kinase-p53 Signaling
Dung-Fang Lee et al.
CELL STEM CELL (2012)
Aurora kinase inhibitors: Progress towards the clinic
Madhu Kollareddy et al.
INVESTIGATIONAL NEW DRUGS (2012)
Nucleophosmin/B23 activates Aurora A at the centrosome through phosphorylation of serine 89
David Reboutier et al.
JOURNAL OF CELL BIOLOGY (2012)
Activation of Aurora-A Is Essential for Neuronal Migration via Modulation of Microtubule Organization
Takako Takitoh et al.
JOURNAL OF NEUROSCIENCE (2012)
Overexpression of Aurora-A Enhances Invasion and Matrix Metalloproteinase-2 Expression in Esophageal Squamous Cell Carcinoma Cells
Xiaoxia Wang et al.
MOLECULAR CANCER RESEARCH (2012)
Aurora-A is an efficient marker for predicting poor prognosis in human nasopharyngeal carcinoma with aggressive local invasion: 208 cases with a 10-year follow-up from a single institution
Zhi-Gang Liu et al.
ONCOLOGY LETTERS (2012)
How protein kinases co-ordinate mitosis in animal cells
Hoi Tang Ma et al.
BIOCHEMICAL JOURNAL (2011)
Mechanisms of aneuploidy
Duane A. Compton
CURRENT OPINION IN CELL BIOLOGY (2011)
Aurora A and Aurora B jointly coordinate chromosome segregation and anaphase microtubule dynamics
Nadia Hegarat et al.
JOURNAL OF CELL BIOLOGY (2011)
Aberrantly expressed AURKC enhances the transformation and tumourigenicity of epithelial cells
Jen-Hui Tsou et al.
JOURNAL OF PATHOLOGY (2011)
Overexpression of Active Aurora-C Kinase Results in Cell Transformation and Tumour Formation
Jabbar Khan et al.
PLOS ONE (2011)
Protein kinases: evolution of dynamic regulatory proteins
Susan S. Taylor et al.
TRENDS IN BIOCHEMICAL SCIENCES (2011)
Crystal structure of an Aurora-A mutant that mimics Aurora-B bound to MLN8054: insights into selectivity and drug design
Charlotte A. Dodson et al.
BIOCHEMICAL JOURNAL (2010)
Significance of Aurora B overexpression in hepatocellular carcinoma. Aurora B Overexpression in HCC
Zhong-Zhe Lin et al.
BMC CANCER (2010)
Aurora-A Is Essential for the Tumorigenic Capacity and Chemoresistance of Colorectal Cancer Stem Cells
Patrizia Cammareri et al.
CANCER RESEARCH (2010)
The chromosome passenger complex is required for fidelity of chromosome transmission and cytokinesis in meiosis of mouse oocytes
Bedra Sharif et al.
JOURNAL OF CELL SCIENCE (2010)
Survivin Reads Phosphorylated Histone H3 Threonine 3 to Activate the Mitotic Kinase Aurora B
Alexander E. Kelly et al.
SCIENCE (2010)
Histone H3 Thr-3 Phosphorylation by Haspin Positions Aurora B at Centromeres in Mitosis
Fangwei Wang et al.
SCIENCE (2010)
Rapid calcium-dependent activation of Aurora-A kinase
Olga V. Plotnikova et al.
NATURE COMMUNICATIONS (2010)
Identification of an Aurora-A/PinsLINKER/Dlg Spindle Orientation Pathway using Induced Cell Polarity in S2 Cells
Christopher A. Johnston et al.
CELL (2009)
Pharmacological inhibition of aurora-A but not aurora-B impairs interphase microtubule dynamics
Corinne Lorenzo et al.
CELL CYCLE (2009)
Making the Auroras glow: regulation of Aurora A and B kinase function by interacting proteins
Mar Carmena et al.
CURRENT OPINION IN CELL BIOLOGY (2009)
Plk1 and Aurora A regulate the depolymerase activity and the cellular localization of Kif2a
Chang-Young Jang et al.
JOURNAL OF CELL SCIENCE (2009)
Aurora-A Kinase Is Essential for Bipolar Spindle Formation and Early Development
Dale O. Cowley et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
An essential role of the aPKC-Aurora A-NDEL1 pathway in neurite elongation by modulation of microtubule dynamics
Daisuke Mori et al.
NATURE CELL BIOLOGY (2009)
Inhibition of Aurora-A suppresses epithelial-mesenchymal transition and invasion by downregulating MAPK in nasopharyngeal carcinoma cells
Xiang-Bo Wan et al.
CARCINOGENESIS (2008)
Linking cell cycle to asymmetric division: Aurora-A phosphorylates the par complex to regulate Numb localization
Frederik Wirtz-Peitz et al.
CELL (2008)
Localization of aurora A and aurora B kinases during interphase
Yoann Rannou et al.
CELL CYCLE (2008)
Plk1 regulates mitotic Aurora A function through βTrCP-dependent degradation of hBora
Eunice H. Y. Chan et al.
CHROMOSOMA (2008)
Centrosome dysfunction in Drosophila neural stem cells causes tumors that are not due to genome instability
Elisabeth Castellanos et al.
CURRENT BIOLOGY (2008)
Aurora A phosphorylates MCAK to control Ran-dependent spindle bipolarity
Xin Zhang et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery
Libor Macurek et al.
NATURE (2008)
Targeted disruption of Aurora A causes abnormal mitotic spindle assembly, chromosome misalignment and embryonic lethality
K. Sasai et al.
ONCOGENE (2008)
Aurora-A and ch-TOG act in a common pathway in control of spindle pole integrity
M. De Luca et al.
ONCOGENE (2008)
A quantitative atlas of mitotic phosphorylation
Noah Dephoure et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
A Cul3-based E3 ligase removes aurora B from mitotic chromosomes, regulating mitotic progression and completion of cytokinesis in human cells
Izabela Sumara et al.
DEVELOPMENTAL CELL (2007)
MLN8054, a small-molecule inhibitor of Aurora A, causes spindle pole and chromosome congression defects leading to aneuploidy
Kara Hoar et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Functional interaction of aurora-A and PP2A during mitosis
Virginie Horn et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
Chromosomes with delayed replication timing lead to checkpoint activation, delayed recruitment of Aurora B and chromosome instability
B. H. Chang et al.
ONCOGENE (2007)
Differential functions of the aurora-B and aurora-C kinases in mammalian spermatogenesis
Sarah Kimmins et al.
MOLECULAR ENDOCRINOLOGY (2007)
Aurora-B expression and its correlation with cell proliferation and metastasis in oral cancer
Guangying Qi et al.
VIRCHOWS ARCHIV (2007)
Asymmetric inheritance of mother versus daughter centrosome in stem cell division
Yukiko M. Yamashita et al.
SCIENCE (2007)
Aurora-A: the maker and breaker of spindle poles
Alexis R. Barr et al.
JOURNAL OF CELL SCIENCE (2007)
Aurora-A acts as a tumor suppressor and regulates self-renewal of Drosophila neuroblasts
Hongyan Wang et al.
GENES & DEVELOPMENT (2006)
Drosophila Aurora-A kinase inhibits neuroblast self-renewal by regulating aPKC/Numb cortical polarity and spindle orientation
Cheng-Yu Lee et al.
GENES & DEVELOPMENT (2006)
Regulation of mitotic chromosome cohesion by Haspin and Aurora B
Jun Dai et al.
DEVELOPMENTAL CELL (2006)
Mitotic activation of the kinase Aurora-A requires its binding partner Bora
Andrea Hutterer et al.
DEVELOPMENTAL CELL (2006)
The chromosomal passenger complex: guiding Aurora-B through mitosis
Gerben Vader et al.
JOURNAL OF CELL BIOLOGY (2006)
Aurora A, mitotic entry, and spindle bipolarity
Q Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Survivin mediates targeting of the chromosomal passenger complex to the centromere and midbody
G Vader et al.
EMBO REPORTS (2006)
The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A
ZS Zhao et al.
MOLECULAR CELL (2005)
Inhibition of Aurora-B kinase activity by poly(ADP-ribosyl)ation in response to DNA damage
L Monaco et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Aurora A activates D-TACC-Msps complexes exclusively at centrosomes to stabilize centrosomal microtubules
TP Barros et al.
JOURNAL OF CELL BIOLOGY (2005)
Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis
K Kinoshita et al.
JOURNAL OF CELL BIOLOGY (2005)
CDC25B phosphorylation by Aurora-A occurs at the G2/M transition and is inhibited by DNA damage
M Cazales et al.
CELL CYCLE (2005)
Aurora kinases
VM Bolanos-Garcia
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2005)
Mechanism of aurora-B degradation and its dependency on intact KEN and A-boxes: Identification of an aneuploidy-promoting property
HG Nguyen et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks
LC Kapitein et al.
NATURE (2005)
Mechanism of Aurora B activation by INCENP and inhibition by Hesperadin
F Sessa et al.
MOLECULAR CELL (2005)
A small C-terminal sequence of Aurora B is responsible for localization and function
L Scrittori et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Aurora B phosphorylates centromeric MCAK and regulates its localization and microtubule depolymerization activity
WJ Lan et al.
CURRENT BIOLOGY (2004)
Aurora-A abrogation of p53 DNA binding and transactivation activity by phosphorylation of serine 215
QY Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Relocation of Aurora B from centromeres to the central spindle at the metaphase to anaphase transition requires MKIp2
U Gruneberg et al.
JOURNAL OF CELL BIOLOGY (2004)
Evolutionary relationships of Aurora kinases: Implications for model organism studies and the development of anti-cancer drugs
JR Brown et al.
BMC EVOLUTIONARY BIOLOGY (2004)
BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition
M Ouchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The cellular geography of aurora kinases
M Carmena et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)
Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells
T Hirota et al.
CELL (2003)
Function and regulation of Aurora/Ipl1p kinase family in cell division
YW Ke et al.
CELL RESEARCH (2003)
CENP-A phosphorylation by Aurora-A in prophase is required for enrichment of Aurora-B inner centromeres and for kinetochore function
N Kunitoku et al.
DEVELOPMENTAL CELL (2003)
The D-Box-activating domain (DAD) is a new proteolysis signal that stimulates the silent D-Box sequence of Aurora-A
A Castro et al.
EMBO REPORTS (2002)
Identification of phosphorylated residues that affect the activity of the mitotic kinase Aurora-A
LE Littlepage et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Human TPX2 is required for targeting Aurora-A kinase to the spindle
TA Kufer et al.
JOURNAL OF CELL BIOLOGY (2002)
Aurora-B associated protein phosphatases as negative regulators of kinase activation
K Sugiyama et al.
ONCOGENE (2002)
APC/Fizzy-Related targets Aurora-A kinase for proteolysis
A Castro et al.
EMBO REPORTS (2002)
Drosophila aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis
D Berdnik et al.
CURRENT BIOLOGY (2002)
Cell-cycle-dependent regulation of human aurora a transcription is mediated by periodic repression of E4TF1
M Tanaka et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells
P Meraldi et al.
EMBO JOURNAL (2002)
Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules
R Giet et al.
JOURNAL OF CELL BIOLOGY (2002)
Mitotic phosphorylation of histone H3: Spatio-temporal regulation by mammalian aurora kinases
C Crosio et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Aurora-A kinase is required for centrosome maturation in Caenorhabditis elegans
E Hannak et al.
JOURNAL OF CELL BIOLOGY (2001)
The zinc finger domain of Tzfp binds to the tbs motif located at the upstream flanking region of the Aie1 (aurora-C) kinase gene
CJC Tang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Regulation of the G2/M transition by p53
WR Taylor et al.
ONCOGENE (2001)
Genomic organization, expression, and chromosome localization of a third aurora-related kinase gene, Aie1
HM Hu et al.
DNA AND CELL BIOLOGY (2000)
TPX2, a novel Xenopus MAP involved in spindle pole organization
T Wittmann et al.
JOURNAL OF CELL BIOLOGY (2000)
The Protein Data Bank
HM Berman et al.
NUCLEIC ACIDS RESEARCH (2000)
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