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注意：仅列出部分参考文献，下载原文获取全部文献信息。Nek6 suppresses the premature senescence of human cancer cells induced by camptothecin and doxorubicin treatment
Hye Jin Jee et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Nek1 kinase functions in DNA damage response and checkpoint control through a pathway independent of ATM and ATR
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Nek9 is a Plk1-activated kinase that controls early centrosome separation through Nek6/7 and Eg5
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EMBO JOURNAL (2011)
Nek10 Mediates G(2)/M Cell Cycle Arrest and MEK Autoactivation in Response to UV Irradiation
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MOLECULAR AND CELLULAR BIOLOGY (2011)
Common Breast Cancer Susceptibility Alleles and the Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Implications for Risk Prediction
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CANCER RESEARCH (2010)
Nek4 Status Differentially Alters Sensitivity to Distinct Microtubule Poisons
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Novel combination treatment for colorectal cancer using Nek2 siRNA and cisplatin
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CANCER SCIENCE (2010)
Nek6 overexpression antagonizes p53-induced senescence in human cancer cells
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CELL CYCLE (2010)
被撤回的出版物: Nek6 Mediates Human Cancer Cell Transformation and Is a Potential Cancer Therapeutic Target(Retracted article. See vol. 15, pg. 358, 2017)
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MOLECULAR CANCER RESEARCH (2010)
Components of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunction
Balca R. Mardin et al.
NATURE CELL BIOLOGY (2010)
Nek7 kinase targeting leads to early mortality, cytokinesis disturbance and polyploidy
H. Salem et al.
ONCOGENE (2010)
Nek2 as a novel molecular target for the treatment of breast carcinoma
Nobuyuki Tsunoda et al.
CANCER SCIENCE (2009)
The Primary Cilium as a Complex Signaling Center
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CURRENT BIOLOGY (2009)
Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2
H. Christian Reinhardt et al.
CURRENT OPINION IN CELL BIOLOGY (2009)
The NIMA-family kinase Nek3 regulates microtubule acetylation in neurons
Jufang Chang et al.
JOURNAL OF CELL SCIENCE (2009)
The Nek6 and Nek7 Protein Kinases Are Required for Robust Mitotic Spindle Formation and Cytokinesis
Laura O'Regan et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
An Autoinhibitory Tyrosine Motif in the Cell-Cycle-Regulated Nek7 Kinase Is Released through Binding of Nek9
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MOLECULAR CELL (2009)
Nip2/Centrobin May Be a Substrate of Nek2 That Is Required for Proper Spindle Assembly During Mitosis in Early Mouse Embryos
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MOLECULAR REPRODUCTION AND DEVELOPMENT (2009)
NEK11 regulates CDC25A degradation and the IR-induced G2/M checkpoint
Marina Melixetian et al.
NATURE CELL BIOLOGY (2009)
Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2
Shahana Ahmed et al.
NATURE GENETICS (2009)
The NIMA-family kinase, Nek1 affects the stability of centrosomes and ciliogenesis
Mark C. White et al.
BMC CELL BIOLOGY (2008)
Never-in-mitosis related kinase 1 functions in DNA damage response and checkpoint control
Yumay Chen et al.
CELL CYCLE (2008)
beta-Catenin is a Nek2 substrate involved in centrosome separation
Shirin Bahmanyar et al.
GENES & DEVELOPMENT (2008)
Nek8 regulates the expression and localization of polycystin-1 and polycystin-2
Eisei Sohara et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2008)
Nek3 kinase regulates prolactin-mediated cytoskeletal reorganization and motility of breast cancer cells
S. L. Miller et al.
ONCOGENE (2007)
Irradiation-induced G2/M checkpoint response requires ERK1/2 activation
Y. Yan et al.
ONCOGENE (2007)
Patterns of somatic mutation in human cancer genomes
Christopher Greenman et al.
NATURE (2007)
Protein phosphatase-1α regulates centrosome splitting through Nek2
Jun Mi et al.
CANCER RESEARCH (2007)
Development of polycystic kidney disease in juvenile cystic kidney mice: Insights into pathogenesis, ciliary abnormalities, and common features with human disease
Laurie A. Smith et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2006)
The when and wheres of CDC25 phosphatases
R Boutros et al.
CURRENT OPINION IN CELL BIOLOGY (2006)
ERK activity facilitates activation of the S-phase DNA damage checkpoint by modulating ATR function
D Wu et al.
ONCOGENE (2006)
NIMA-related kinases defective in murine models of polycystic kidney diseases localize to primary cilia and centrosomes
MR Mahjoub et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2005)
Caught Nek-ing: cilia and centrioles
LM Quarmby et al.
JOURNAL OF CELL SCIENCE (2005)
Rootletin forms centriole-associated filaments and functions in centrosome cohesion
S Bahe et al.
JOURNAL OF CELL BIOLOGY (2005)
Cilia and disease
L Eley et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2005)
BRCA1-mediated G2/M cell cycle arrest requires ERK1/2 kinase activation
Y Yan et al.
ONCOGENE (2005)
MAPKAP kinase-2 is a cell cycle checkpoint kinase that regulates the G2/M transition and S phase progression in response to UV irradiation
IA Manke et al.
MOLECULAR CELL (2005)
Accelerated MDM2 auto-degradation induced by DNA-damage kinases is required for p53 activation
JM Stommel et al.
EMBO JOURNAL (2004)
Nek2A specifies the centrosomal localization of Erk2
Y Lou et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
NIMA-related protein kinase 1 is involved early in the ionizing radiation-induced DNA damage response
R Polci et al.
CANCER RESEARCH (2004)
Potential link between the NIMA mitotic kinase and nuclear membrane fission during mitotic exit in Aspergillus nidulans
JR Davies et al.
EUKARYOTIC CELL (2004)
Suppression of Nek2A in mouse early embryos confirms its requirement for chromosome segregation
S Sonn et al.
JOURNAL OF CELL SCIENCE (2004)
Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints
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ANNUAL REVIEW OF BIOCHEMISTRY (2004)
NEK2A interacts with MAD1 and possibly functions as a novel integrator of the spindle checkpoint signaling
Y Lou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
SCFβ-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase
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GENES & DEVELOPMENT (2003)
A mitotic cascade of NIMA family kinases - Nercc1/Nek9 activates the Nek6 and Nek7 kinases
C Belham et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Nek2A kinase stimulates centrosome disjunction and is required for formation of bipolar mitotic spindles
AJ Faragher et al.
MOLECULAR BIOLOGY OF THE CELL (2003)
Never say never. The NIMA-related protein kinases in mitotic control
MJ O'Connell et al.
TRENDS IN CELL BIOLOGY (2003)
A defect in a novel Nek-family kinase causes cystic kidney disease in the mouse and in zebrafish
SM Liu et al.
DEVELOPMENT (2002)
Molecular basis for the substrate specificity of NIMA-related kinase-6 (NEK6) -: Evidence that NEK6 does not phosphorylate the hydrophobic motif of ribosomal S6 protein kinase and serum- and glucocorticoid-induced protein kinase in vivo
JM Lizcano et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Nercc1, a mammalian NIMA-family kinase, binds the Ran GTPase and regulates mitotic progression
J Roig et al.
GENES & DEVELOPMENT (2002)
The related murine kinases, Nek6 and Nek7, display distinct patterns of expression
E Feige et al.
MECHANISMS OF DEVELOPMENT (2002)
Identification of the NIMA family kinases NEK6/7 as regulators of the p70 ribosomal S6 kinase
C Belham et al.
CURRENT BIOLOGY (2001)
Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase
DV Bulavin et al.
NATURE (2001)
Mitotic histone H3 phosphorylation by the NIMA kinase in Aspergillus nidulans
CPC De Souza et al.
CELL (2000)
Mutations in a NIMA-related kinase gene, Nek1, cause pleiotropic effects including a progressive polycystic kidney disease in mice
P Upadhya et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
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