期刊
ONCOTARGETS AND THERAPY
卷 7, 期 -, 页码 1111-1114出版社
DOVE MEDICAL PRESS LTD
DOI: 10.2147/OTT.S64706
关键词
hepatocellular carcinoma; recall radiation dermatitis
资金
- Far Eastern Memorial Hospital [FEMH-2014-C-045, FEMH 101-2314-B-418-010-MY3]
We report on a 63-year-old man with a history of hepatitis B virus-related hepatocellular carcinoma with a thrombus extending into the inferior vena cava, who received image-guided stereotactic body radiation therapy (SBRT) with helical tomotherapy, followed by sorafenib. A total tumor dose of 48 Gy was delivered by 6 fractions within 2 weeks. The tumor responded dramatically, and the patient tolerated the courses well. Ten days after SBRT, sorafenib (200 mg), at 1.5 tablets twice a day, was prescribed. One week later, grade 2 recall radiation dermatitis subsequently developed in the previous SBRT off-target area. SBRT followed by sorafenib for the treatment of a portal vein thrombosis provided effective results, but the potential risk of enhanced adverse effects between radiation and sorafenib should be considered with caution, especially under a SBRT scheme.
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