相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Murgocil is a Highly Bioactive Staphylococcal-Specific Inhibitor of the Peptidoglycan Glycosyltransferase Enzyme MurG
Paul A. Mann et al.
ACS CHEMICAL BIOLOGY (2013)
Selective inhibition of glycosyltransferases by bivalent imidazolium salts
Yin Gao et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2013)
Development of fucosyltransferase and fucosidase inhibitors
Zhijay Tu et al.
CHEMICAL SOCIETY REVIEWS (2013)
Design of Glycosyltransferase Inhibitors: Pyridine as a Pyrophosphate Surrogate
Shuai Wang et al.
CHEMISTRY-A EUROPEAN JOURNAL (2013)
Base-modified Donor Analogues Reveal Novel Dynamic Features of a Glycosyltransferase
Rene Jorgensen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
A Nonionic Inhibitor with High Specificity for the UDP-Gal Donor Binding Site of Human Blood Group B Galactosyltransferase: Design, Synthesis, and Characterization
Katrin Schaefer et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Toward Analogues of MraY Natural Inhibitors: Synthesis of 5′-Triazole-Substituted-Aminoribosyl Uridines Through a Cu-Catalyzed Azide-Alkyne Cycloaddition
Mickael J. Fer et al.
JOURNAL OF ORGANIC CHEMISTRY (2013)
C-Branched Iminosugars: α-Glucosidase Inhibition by Enantiomers of isoDMDP, isoDGDP, and isoDAB-L-isoDMDP Compared to Miglitol and Miglustat
Sarah F. Jenkinson et al.
JOURNAL OF ORGANIC CHEMISTRY (2013)
A Glycosyltransferase Inhibitor from a Molecular Fragment Library Simultaneously Interferes with Metal Ion and Substrate Binding
Rene Jorgensen et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)
SQ109 Targets MmpL3, a Membrane Transporter of Trehalose Monomycolate Involved in Mycolic Acid Donation to the Cell Wall Core of Mycobacterium tuberculosis
Kapil Tahlan et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2012)
Sialic acid metabolism and sialyltransferases: natural functions and applications
Yanhong Li et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2012)
A New Concept for Glycosyltransferase Inhibitors: Nonionic Mimics of the Nucleotide Donor of the Human Blood Group B Galactosyltransferase
Katrin Schaefer et al.
CHEMBIOCHEM (2012)
Recent structures, evolution and mechanisms of glycosyltransferases
Christelle Breton et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2012)
Discovery and development of SQ109: a new antitubercular drug with a novel mechanism of action
Katherine A. Sacksteder et al.
FUTURE MICROBIOLOGY (2012)
Miglustat as a therapeutic agent: prospects and caveats
Rosemarie E. Venier et al.
JOURNAL OF MEDICAL GENETICS (2012)
Discovery and Characterization of an Inhibitor of Glucosylceramide Synthase
Steven Richards et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Galvestine-1, a novel chemical probe for the study of the glycerolipid homeostasis system in plant cells
Laurence Boudiere et al.
MOLECULAR BIOSYSTEMS (2012)
A neutral diphosphate mimic crosslinks the active site of human O-GlcNAc transferase
Jiaoyang Jiang et al.
NATURE CHEMICAL BIOLOGY (2012)
Global metabolic inhibitors of sialyl- and fucosyltransferases remodel the glycome
Cory D. Rillahan et al.
NATURE CHEMICAL BIOLOGY (2012)
Safety, Tolerability, and Pharmacokinetics of Eliglustat Tartrate (Genz-112638) After Single Doses, Multiple Doses, and Food in Healthy Volunteers
M. Judith Peterschmitt et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2011)
Hijacking a biosynthetic pathway yields a glycosyltransferase inhibitor within cells
Tracey M. Gloster et al.
NATURE CHEMICAL BIOLOGY (2011)
Chemical inhibitors of monogalactosyldiacylglycerol synthases in Arabidopsis thaliana
Cyrille Y. Botte et al.
NATURE CHEMICAL BIOLOGY (2011)
A Glucosylceramide Synthase Inhibitor Protects Rats Against the Cytotoxic Effects of Shiga Toxin 2
Claudia Silberstein et al.
PEDIATRIC RESEARCH (2011)
A haploid genetic screen identifies the major facilitator domain containing 2A (MFSD2A) transporter as a key mediator in the response to tunicamycin
Jan H. Reiling et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Glycosyltransferases and their Assays
Gerd K. Wagner et al.
CHEMBIOCHEM (2010)
A Novel Fluorescent Probe for Retaining Galactosyltransferases
Thomas Pesnot et al.
CHEMBIOCHEM (2010)
New structures, chemical functions, and inhibitors for glycosyltransferases
Rajarshi Roychoudhury et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2010)
The chemical biology of new drugs in the development for tuberculosis
Clifton E. Barry et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2010)
NMR-based exploration of the acceptor binding site of human blood group B galactosyltransferase with molecular fragments
Christoph Rademacher et al.
GLYCOCONJUGATE JOURNAL (2010)
Reducing glycosphingolipid biosynthesis in airway cells partially ameliorates disease manifestations in a mouse model of asthma
Jozsef Karman et al.
INTERNATIONAL IMMUNOLOGY (2010)
New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays
Jonathan B. Baell et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
UDP-(5F)-GlcNAc Acts as a Slow-Binding Inhibitor of MshA, a Retaining Glycosyltransferase
Patrick A. Frantom et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
Exploring genomes for glycosyltransferases
Sara Fasmer Hansen et al.
MOLECULAR BIOSYSTEMS (2010)
Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis
Jose A. Caminero et al.
LANCET INFECTIOUS DISEASES (2010)
Structural and mechanistic basis for a new mode of glycosyltransferase inhibition
Thomas Pesnot et al.
NATURE CHEMICAL BIOLOGY (2010)
Inhibition of glucosylceramide accumulation results in effective blockade of polycystic kidney disease in mouse models
Thomas A. Natoli et al.
NATURE MEDICINE (2010)
Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1
S. A. Caldwell et al.
ONCOGENE (2010)
Identification and characterization of flavonoids as sialyltransferase inhibitors
Kazuya I. P. J. Hidari et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
First small molecular inhibitors of T. brucei dolicholphosphate mannose synthase (DPMS), a validated drug target in African sleeping sickness
Terry K. Smith et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
Rhodanine as a Privileged Scaffold in Drug Discovery
T. Tomasic et al.
CURRENT MEDICINAL CHEMISTRY (2009)
Bisubstrate Analogues as Glycosyltransferase Inhibitors
Masayuki Izumi et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2009)
Mechanism-Based Probing, Characterization, and Inhibitor Design of Glycosidases and Glycosyltransferases
Hiroshi Hinou et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2009)
Deoxygenated Disaccharide Analogs as Specific Inhibitors of β1-4-Galactosyltransferase 1 and Selectin-mediated Tumor Metastasis
Jillian R. Brown et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Synthesis of Glycosyltransferase Inhibitors
Tetsuya Kajimoto et al.
SYNTHESIS-STUTTGART (2009)
Glycosyltransferases: Structures, functions, and mechanisms
L. L. Lairson et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2008)
Design, synthesis, and evaluation of novel ethambutol analogues
Raghunandan Yendapally et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
Discovery of new Gram-negative antivirulence drugs:: Structure and properties of novel E-coli WaaC inhibitors
F. Moreau et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
N-Glycans in cancer progression
Ken S. Lau et al.
GLYCOBIOLOGY (2008)
A strategy to discover inhibitors of O-linked glycosylation
Benjamin J. Gross et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Glycan antagonists and inhibitors: A fount for drug discovery
Jillian R. Brown et al.
CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2007)
Oleic acid: An efficient inhibitor of glucosyltransferase
Se-Ra Won et al.
FEBS LETTERS (2007)
Conformational changes induced by binding UDP-2F-galactose to α-1,3-galactosyltransferase -: Implications for catalysis
Haryati Jamaluddin et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
Inhibiting glycosphingolipid synthesis improves glycemic control and insulin sensitivity in animal models of type 2 diabetes
Hongmei Zhao et al.
DIABETES (2007)
Cycling of O-linked β-N-acetylglucosamine on nucleocytoplasmic proteins
Gerald W. Hart et al.
NATURE (2007)
Synthesis of the antifungal β-1,3-glucan synthase inhibitor CANCIDAS (caspofungin acetate) from pneumocandin B0
William R. Leonard et al.
JOURNAL OF ORGANIC CHEMISTRY (2007)
Two galactosyltransferases' selection of different binders from the same uridine-based dynamic combinatorial library
Anne Valade et al.
JOURNAL OF COMBINATORIAL CHEMISTRY (2007)
Role of lgtC in resistance of nontypeable Haemophilus influenzae strain R2866 to human serum
Alice L. Erwin et al.
INFECTION AND IMMUNITY (2006)
Selectins and glycosyltransferases in leukocyte rolling in vivo
Markus Sperandio
FEBS JOURNAL (2006)
Target-assisted selection of galactosyltransferase binders from dynamic combinatorial libraries. An unexpected solution with restricted amounts of the enzyme
Anne Valade et al.
CHEMBIOCHEM (2006)
Lithocholic acid analogues, new and potent α-2,3-sialyltransferase inhibitors
KH Chang et al.
CHEMICAL COMMUNICATIONS (2006)
Structures and mechanisms of glycosyltransferases
C Breton et al.
GLYCOBIOLOGY (2006)
Discovery of O-GlcNAc transferase inhibitors
BJ Gross et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
Imino sugar inhibitors for treating the lysosomal glycosphingolipidoses
TD Butters et al.
GLYCOBIOLOGY (2005)
Rational design, synthesis, and characterization of novel inhibitors for human β1,4-galactosyltransferase
K Takaya et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Stachybotrydial, a potent inhibitor of fucosyltransferase and sialyltransferase
TW Lin et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Design and synthesis of iminosugar-based inhibitors of glucosylceramide synthase: the search for new therapeutic agents against Gaucher disease
C Boucheron et al.
TETRAHEDRON-ASYMMETRY (2005)
Scintillation proximity assay for inhibitors of Escherichia coli MurG and, optionally, MraY
S Ravishankar et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2005)
Substrate-induced conformational changes in glycosyltransferases
PK Qasba et al.
TRENDS IN BIOCHEMICAL SCIENCES (2005)
Identification of selective inhibitors for the glycosyltransferase via high-throughput murG screening
Y Hu et al.
CHEMISTRY & BIOLOGY (2004)
The transcriptional responses of Mycobacterium tuberculosis to inhibitors of metabolism -: Novel insights into drug mechanisms of action
HIM Boshoff et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Rhodanine-3-acetic acid derivatives as inhibitors of fungal protein mannosyl transferase 1 (PMT1)
MG Orchard et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2004)
O-GlcNAc a sensor of cellular state:: the role of nucleocytoplasmic glycosylation in modulating cellular function in response to nutrition and stress
NE Zachara et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2004)
Inhibition of fucosyltransferase VII by gallic acid and its derivatives
XD Niu et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2004)
Identification of active-site inhibitors of MurG using a generalizable, high-throughput glycosyltransferase screen
JS Helm et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
Membrane disruption and cytotoxicity of hydrophobic N-alkylated imino sugars is independent of the inhibition of protein and lipid glycosylation
HR Mellor et al.
BIOCHEMICAL JOURNAL (2003)
A potent and highly selective inhibitor of human α-1,3-fucosyltransferase via click chemistry
LV Lee et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
A high-throughput solid-phase extraction assay capable of measuring diverse polyprenyl transferases as exemplified by the phosphate: sugar-1-phosphate WecA, MraY, and MurG proteins
SA Hyland et al.
ANALYTICAL BIOCHEMISTRY (2003)
Targeting the MraY and MurG bacterial enzymes for antimicrobial therapeutic intervention
LE Zawadzke et al.
ANALYTICAL BIOCHEMISTRY (2003)
Design, synthesis and biological evaluation of iminosugar-based glycosyltransferase inhibitors
P Compain et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2003)
The hexapeptide inhibitor of Galβ1,3GalNAc-specific α2,3-sialyltransferase as a generic inhibitor of sialyltransferases
KY Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Alloxan is an inhibitor of the enzyme O-linked N-acetylglucosamine transferase
RJ Konrad et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
The emerging significance of O-GlcNAc in cellular regulation
NE Zachara et al.
CHEMICAL REVIEWS (2002)
Homology between O-linked GlcNAc transferases and proteins of the glycogen phosphorylase superfamily
JO Wrabl et al.
JOURNAL OF MOLECULAR BIOLOGY (2001)
Combinatorial library of five-membered iminocyclitol and the inhibitory activities against glyco-enzymes
C Saotome et al.
CHEMISTRY & BIOLOGY (2001)
Crystal structure of the retaining galactosyltransferase LgtC from Neisseria meningitidis in complex with donor and acceptor sugar analogs
K Persson et al.
NATURE STRUCTURAL BIOLOGY (2001)
The effect of the echinocandin analogue caspofungin on cell wall glucan synthesis by Cryptococcus neoformans
M Feldmesser et al.
JOURNAL OF INFECTIOUS DISEASES (2000)
Discovery of novel antifungal (1,3)-β-D-glucan synthase inhibitors
J Onishi et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2000)
Molecular requirements of imino sugars for the selective control of N-linked glycosylation and glycosphingolipid biosynthesis
TD Butters et al.
TETRAHEDRON-ASYMMETRY (2000)
分享论文
