相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。In Silico Fragment-Based Drug Discovery: Setup and Validation of a Fragment-to-Lead Computational Protocol Using S4MPLE
Laurent Hoffer et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2013)
Design, synthesis and molecular modelling of novel methyl[4-oxo-2-(aroylimino)-3-(substituted phenyl)thiazolidin-5-ylidene]acetates as potent and selective aldose reductase inhibitors
Sher Ali et al.
MEDCHEMCOMM (2012)
Aldose Reductase and Cardiovascular Diseases, Creating Human-Like Diabetic Complications in an Experimental Model
Ravichandran Ramasamy et al.
CIRCULATION RESEARCH (2010)
Aldose reductase: A novel therapeutic target for inflammatory pathologies
Kota V. Ramana et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2010)
A Diverse Series of Substituted Benzenesulfonamides as Aldose Reductase Inhibitors with Antioxidant Activity: Design, Synthesis, and in Vitro Activity
Polyxeni Alexiou et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Aldose Reductase Enzyme and its Implication to Major Health Problems of the 21st Century
Polyxeni Alexiou et al.
CURRENT MEDICINAL CHEMISTRY (2009)
AutoDock4 and AutoDockTools4: Automated Docking with Selective Receptor Flexibility
Garrett M. Morris et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2009)
Design and synthesis of N-( 3,5-difluoro-4-hydroxyphenyl) benzenesulfonamides as aldose reductase inhibitors
Polyxeni Alexiou et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2008)
Emerging drugs for diabetic retinopathy
Quresh Mohamed et al.
EXPERT OPINION ON EMERGING DRUGS (2008)
Selectivity determinants of the aldose and aldehyde reductase inhibitor-binding sites
O. El-Kabbani et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2007)
Permeability characteristics of novel aldose reductase inhibitors using rat jejunum in vitro
K Sturm et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2006)
In vitro aldose reductase inhibitory activity of 5-benzyl-2,4-thiazolidinediones
D Rakowitz et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2006)
Factorizing selectivity determinants of inhibitor binding toward aldose and aldehyde reductases: Structural and thermodynamic properties of the aldose reductase mutant Leu300Pro-fidarestat complex
T Petrova et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: Implications for inhibitor binding and selectivity
O El-Kabbani et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Spirohydantoin derivatives of thiopyrano[2,3-b]pyridin-4(4H)-one as potent in vitro and in vivo aldose reductase inhibitors
F Da Settimo et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2005)
Ultrahigh resolution drug design I:: Details of interactions in human aldose reductase-inhibitor complex at 0.66 Å
EI Howard et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2004)
[1-(3,5-Difluoro-4-hydroxyphenyl)-1H-pyrrol-3-yl]phenylmethanone as a bioisostere of a carboxylic acid aldose reductase inhibitor
L Nicolaou et al.
JOURNAL OF MEDICINAL CHEMISTRY (2004)
Structure of human aldose reductase holoenzyme in complex with statil: An approach to structure-based inhibitor design of the enzyme
O El-Kabbani et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2003)
Molecular understanding of hyperglycemia's adverse effects for diabetic complications
MJ Sheetz et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2002)
Recent advances in aldose reductase inhibitors: potential agents for the treatment of diabetic complications
S Miyamoto
EXPERT OPINION ON THERAPEUTIC PATENTS (2002)
Biochemistry and molecular cell biology of diabetic complications
M Brownlee
NATURE (2001)
Aldose reductase does catalyse the reduction of glyceraldehyde through a stoichiometric oxidation of NADPH
A Del Corso et al.
EXPERIMENTAL EYE RESEARCH (2000)