4.1 Article

Imidazolium salts as antifungal agents: activity against emerging yeast pathogens, without human leukocyte toxicity

期刊

MEDCHEMCOMM
卷 4, 期 11, 页码 1457-1460

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c3md00222e

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  1. Brazilian agency CAPES
  2. Brazilian agency CNPq
  3. Brazilian agency FAPERGS
  4. FAPERGS-CAPES

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This study demonstrates the excellent in vitro antifungal activity profile of imidazolium ionic liquids (ILs) against species of opportunistic human mycoses. Several ILs were identified as more effective and less harmful than commercially available antifungal medications. Frequently, emerging yeast pathogens are resistant against commercial antifungal agents and, as a consequence, this class of imidazolium ILs represents a promising breakthrough in their treatment.

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