期刊
MEDCHEMCOMM
卷 3, 期 11, 页码 1462-1465出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2md20244a
关键词
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资金
- National Institutes of Health [GM055769]
- Glaxo Smith Kline
A diverse 23-compound library of N-1 substituted 2-aminobenzimidazoles was synthesized via an efficient three-step process. This small library produced several non-toxic biofilm modulators of two strains of MRSA. Preliminary mechanistic studies reveal a zinc-dependent mode of action for these compounds.
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