期刊
CURRENT OPINION IN ENDOCRINOLOGY DIABETES AND OBESITY
卷 19, 期 3, 页码 228-232出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MED.0b013e3283537cb8
关键词
cryptorchidism; hypospadias; semen quality; smoking; testicular cancer
资金
- Academy of Finland
- Turku University Hospital
- Sigrid Juselius Foundation
- European Commission [QLK4-CT-1999-01422, QLK4-CT-2001-00269, QLK4-2002-00603]
- Danish Council for Strategic Research
Purpose of review To assess whether prenatal exposure to smoking is associated with impaired reproductive health in exposed men. Recent findings Men who have been exposed to maternal smoking in utero have smaller testes and impaired semen quality as compared to nonexposed men, suggesting toxic effects on Sertoli and/or germ cells. According to meta-analyses there is only a weak or no association with fetal exposure to smoking and the incidence of testicular germ cell cancer, cryptorchidism, or hypospadias. Summary Adverse effect of maternal smoking on sperm production capacity of their son is yet another good reason for women to quit smoking before pregnancy.
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