期刊
ENVIRONMENTAL MICROBIOLOGY REPORTS
卷 6, 期 3, 页码 212-225出版社
WILEY
DOI: 10.1111/1758-2229.12130
关键词
-
资金
- Intramural Research Program of the National Institutes of Health
- National Cancer Institute
- Center for Cancer Research
Although prokaryotes ordinarily undergo binary fission to produce two identical daughter cells, some are able to undergo alternative developmental pathways that produce daughter cells of distinct cell morphology and fate. One such example is a developmental programme called sporulation in the bacterium Bacillus subtilis, which occurs under conditions of environmental stress. Sporulation has long been used as a model system to help elucidate basic processes of developmental biology including transcription regulation, intercellular signalling, membrane remodelling, protein localization and cell fate determination. This review highlights some of the recent work that has been done to further understand prokaryotic cell differentiation during sporulation and its potential applications.
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