期刊
JOURNAL OF MATERIALS CHEMISTRY B
卷 3, 期 15, 页码 2931-2934出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5tb00063g
关键词
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资金
- Natural Science Foundation of China [91326202, 21174100, 31270897]
- Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)
- Qing-Lan Project of Jiangsu Province
- Jiangsu Key Laboratory of Radiation Medicine and Protection
We demonstrate a strategy for effective radioprotection by chitosan-based long-circulating nanocarriers with radio-protective agents. The stable encapsulation does not restrain its radioprotective capability, and exhibits prolonged retention time in blood with a half-life of similar to 10 h, thereby showing more beneficial effects than the pure agent in therapeutic efficacy for irradiated mice.
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