期刊
CHEMICAL SCIENCE
卷 5, 期 6, 页码 2123-2134出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3sc52768a
关键词
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资金
- NWO VICI grant
- Ministry of Education, Culture and Science [024.001.035]
Bioorthogonal chemistry allows for selective and efficient modification of biomolecules in their natural environment. Several strategies have been developed over the past years that employ cellular biosynthetic pathways to incorporate the desired functionalities. These moieties in turn efficiently react with exogenously added complementary reaction partners. This field has now moved forward from a conceptual phase to the application of these methodologies in living systems. In this perspective, we highlight recent and exciting developments pertaining to the use of bioorthogonal chemistry in living organisms.
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