期刊
CHEMICAL SCIENCE
卷 5, 期 6, 页码 2422-2427出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4sc00697f
关键词
-
资金
- NSF [CHE-1152767]
- NIH [R01-GM098777]
- Division Of Chemistry
- Direct For Mathematical & Physical Scien [1152767, 1624211] Funding Source: National Science Foundation
The Co(II) complex of the D-2h-symmetric amidoporphyrin 3,5-DitBu-IbuPhyrin, [Co(P1)], has proven to be an effective metalloradical catalyst for intermolecular amination of C(sp(2))-H bonds of aldehydes with fluoroaryl azides. The [Co(P1)]-catalyzed process can employ aldehydes as the limiting reagents and operate under neutral and nonoxidative conditions, generating nitrogen gas as the only byproduct. The metalloradical aldehydic C-H amination is suitable for different combinations of aldehydes and fluoroaryl azides, producing the corresponding N-fluoroaryl amides in good to excellent yields. A series of mechanistic studies support a stepwise radical mechanism for the Co(II)-catalyzed intermolecular C-H amination.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据