期刊
CHEMICAL SCIENCE
卷 3, 期 11, 页码 3280-3285出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2sc21068a
关键词
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资金
- Spanish Ministry of Economy and Competitivity (MEC)
- ERDF [CTQ2010-15725, CSD2007-00006]
- Xunta de Galicia [GRC2006/132]
- European project Magnifyco [NMP4-SL-2009-228622]
- Spanish MICINN
In this study, we describe the self-assembling properties of cyclic peptides containing gamma-amino acids in lipid bilayers to form transmembrane nanotubes. The resulting ion channel models are selective for alkaline ions. Although the transport rates conform to the lyotropic series, these partially hydrophobic channels show an unexpectedly higher rate for sodium ions.
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