期刊
CHEMICAL SCIENCE
卷 3, 期 5, 页码 1422-1425出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2sc20111a
关键词
-
资金
- Swiss National Science Foundation [200020_134682/1]
- Swiss National Science Foundation (SNF) [200020_134682] Funding Source: Swiss National Science Foundation (SNF)
N-Aryl, N-branched alkyl carbamates react with in situ generated chiral Pd-NHC catalysts by coupling a Pd-Ar moiety with an aliphatic C-H bond at high temperature to give enantioenriched 2-substituted and 2,3-disubstituted indolines. Prochiral precursors give single products with very high asymmetric induction. Chiral racemic precursors react in a regiodivergent reaction of a racemic mixture to yield enantioenriched indolines resulting from either methyl C-H activation or asymmetric methylene C-H activation. In favorable cases this can result in a complete separation of an enatiomeric mixture into two different highly enantioenriched indolines.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据