4.8 Article

A fluorescent probe for rapid detection of hydrogen sulfide in blood plasma and brain tissues in mice

期刊

CHEMICAL SCIENCE
卷 3, 期 10, 页码 2920-2923

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c2sc20537h

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资金

  1. National Basic Research Program of China [2010CB923303]
  2. Program for New Century Excellent Talents in University
  3. National Natural Science Foundation of China [20902045, 91013009]
  4. Natural Science Foundation of Jiangsu Province [BK2011547]

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We describe the design, synthesis and application of a sensitive, selective, and fast fluorescent probe for H2S detection. A linear relationship between emission intensity and sulfide concentration was observed in biological bovine plasma systems. With this probe, we were able to estimate the sulfide concentration in mouse blood plasma and brain tissues.

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