期刊
JOURNAL OF MATERIALS CHEMISTRY B
卷 3, 期 22, 页码 4539-4545出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5tb00560d
关键词
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资金
- National Basic research Program of China (973 Program) [2013CB932802]
- National Nature Science Foundation of China [21433010, 21321063, 21303219, 51303038, 21273250]
A core-shell composite consisting of polypyrrole (PPy) coating on Au nanorods with high two-photon photothermal efficiency and good photostability have been fabricated via a facile interfacial polymerization. Transmission electron microscopy confirmed the core-shell structure of the uniform Au-PPy nanorods. The core-shell composites exhibited improved temperature elevation and photostability compared to pure Au nanorods. The composites internalized by cancer cells can be detected by strong two-photon fluorescence, thus minimizing photothermal damage to normal tissues. The cell cytotoxicity and two-photon efficiency experiments in vitro demonstrate that the composites of Au-PPy nanorods have high efficiency to inhibit the proliferation of tumor cells.
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