Antidiarrhoeal efficacy of Mangifera indica seed kernel on Swiss albino mice

Objective: To examine the antidiarrhoeal activity of alcoholic and aqueous seed kernel extract of Mangifera indica (M. indica) on castor oil-induce diarrhoeal activity in Swiss albino mice. Methods: Mango seed kernels were processed and extracted using alcohol and water. Antidiarrhoeal activity of the extracts were assessed using intestinal motility and faecal score methods. Results: Aqueous and alcoholic extracts of M. indica significantly reduced intestinal motility and faecal score in Swiss albino mice. Conclusions: The present study shows the traditional claim on the use of M. indica seed kernel for treating diarrhoea in Southern parts of India.