期刊
ANNALI DELL ISTITUTO SUPERIORE DI SANITA
卷 48, 期 4, 页码 407-414出版社
PENSIERO SCIENTIFICO EDITORE
DOI: 10.4415/ANN_12_04_08
关键词
Ostreopsis; palytoxin (PLTX); acute toxicity; myotoxicity; cutaneous toxicity
资金
- Italian Ministry of Education University and Research [PRIN2009JS5YX9_002]
- Regione Friuli-Venezia Giulia, Direzione Risorse Rurali, Agroalimentari e Forestali (Progetto Kit e biosensori di elevata sensibilita per la determinazione delle tossine di alghe nelle acque e nei prodotti ittici del Friuli-Venezia Giulia - Senstox)
The increased presence of potentially toxic microalgae in the Mediterranean area is a matter of great concern. Since the end of the last century, microalgae of the genus Ostreopsis have been detected more and more frequently in the Italian coastal waters. The presence of Ostreopsis spp. has been accompanied by the presence of previously undetected marine biotoxins (palytoxins) into the ecosystem with the increased possibility of human exposure. In response to the urgent need for toxicity characterization of palytoxin and its congeners, an integrated study encompassing both in vitro and in vivo methods was performed.
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