期刊
VIRUSES-BASEL
卷 3, 期 3, 页码 254-259出版社
MDPI
DOI: 10.3390/v3030254
关键词
HTLV-1; HIV-1; cell-to-cell transfer; virological synapses; cellular conduits; p8; p12; Nef
类别
Retroviruses like HIV-1 and HTLV-1 can be transmitted efficiently by direct contact between infected and target cells. For HIV-1, various modes of cell-to-cell transfer have been reported, including virological synapses, polysynapses, filopodial bridges, and nanotube-like structures. So far, only synapses and biofilms have been described for HTLV-1 transmission. Recently, Van Prooyen et al. [1] identified an additional mode of HTLV-1 transmission through cellular conduits induced by the viral accessory protein p8.
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