期刊
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES
卷 69, 期 3-4, 页码 117-123出版社
VERLAG Z NATURFORSCH
DOI: 10.5560/ZNC.2013-0088
关键词
Red Sea; Marine Sponges; Breast Cancer
资金
- Saudi Basic Industries Corporation (SABIC)
- Deanship of Scientific Research (DSR), King Abdulaziz University, Jeddah, Saudi Arabia [MS/14/252/1433]
- SABIC
- DSR
Two new polyacetylenes, callyspongenol-D (1) and callyspongendiol (2), the known polyacetylene dehydrosiphonochalynol (3), and the known triterpenoid sipholenol-A (4) were isolated from the Red Sea sponge Siphonochalina siphonella. Their chemical structures were elucidated on the basis of spectroscopic analyses. The cytotoxicity of the isolated compounds towards the human mammary carcinoma cell line MCF-7 was determined by the lactate dehydrogenase (LDH) assay, and compounds 4 and 1 were found to be the most toxic of the four, with IC50 values of 8.8 and 11.7 mu m, respectively.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据