期刊
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES
卷 64, 期 3, 页码 313-318出版社
WALTER DE GRUYTER GMBH
DOI: 10.1515/znb-2009-0310
关键词
Isocoumarin; Dihydroisocoumarin; Sonogashira Reaction; Hydrogenation; Cytotoxic Activity
3-Substituted isocoumarins were Prepared in a short and efficient way from 2-iodobenzoic acid and terminal alkynes in a one-pot Sonogashira reaction. Catalytic hydrogenation gave the corresponding dihydroisocoumarins. The cytotoxic activities of the resulting compounds against human leukaemia cell line (HL60) were determined in a MTT assay, and structure-activity relationships are discussed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据