期刊
JOURNAL OF THE AMERICAN HEART ASSOCIATION
卷 4, 期 3, 页码 -出版社
WILEY
DOI: 10.1161/JAHA.114.001379
关键词
accelerometry; physical activity; visceral adipose tissue
资金
- National Heart, Lung and Blood Institute's Framingham Heart Study [N01-HC-25195]
- [R01AG047645]
- DIVISION OF EPIDEMIOLOGY AND CLINICAL APPLICATIONS [N01HC025195] Funding Source: NIH RePORTER
- NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [ZIAHL006094] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE ON AGING [R01AG047645] Funding Source: NIH RePORTER
Background-We examined the relation between objectively measured physical activity with accelerometry and subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) in a community-based sample. Methods and Results-We evaluated 1249 participants of the Framingham Third Generation and Omni II cohorts (mean age 51.7 years, 47% women) who underwent assessment of moderate-to-vigorous physical activity (MVPA) with accelerometry over 5 to 7 days, and multi-detector computed tomography for measurement of SAT and VAT volume; fat attenuation was estimated by SAT and VAT hounsfield units (HU). In women, higher levels of MVPA were associated with decreased SAT (P<0.0001) and VAT volume (P<0.0001). The average decrement in VAT per 30 minute/day increase in MVPA was -453 cm(3) (95% CI-574, -331). The association was attenuated but persisted upon adjustment for BMI (-122 cm(3), P=0.002). Higher levels of MVPA were associated with higher SAT HU (all P <= 0.01), a marker of fat quality, even after adjustment for SAT volume. Similar findings were observed in men but the magnitude of the association was less. Sedentary time was not associated with SAT or VAT volume or quality in men or women. Conclusions-MVPA was associated with less VAT and SAT and better fat quality.
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