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J. Dunn et al.
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Koichi Ichimura et al.
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Joerg Balss et al.
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Alba A. Brandes et al.
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Nomograms for predicting survival of patients with newly diagnosed glioblastoma: prognostic factor analysis of EORTC and NCIC trial 26981-22981/CE.3
Thierry Gorlia et al.
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D. Williams Parsons et al.
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Ulrich Herrlinger et al.
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W Stummer et al.
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ME Hegi et al.
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Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
R Stupp et al.
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Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents
M Esteller et al.
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