期刊
WORLD JOURNAL OF PEDIATRICS
卷 6, 期 2, 页码 154-157出版社
ZHEJIANG UNIV SCH MEDICINE
DOI: 10.1007/s12519-010-0030-5
关键词
candidal sepsis; extremely low birth weight; peripherally inserted central catheters; premature infants; very low birth weight
类别
资金
- National Natural Science Foundation of China [30825039, 30770748]
- China Medical Board of New York [00-722]
Background: Peripherally inserted central catheters (PICCs) have been widely used in neonatal clinics. However, the complications such as infection after PICC treatment are also confronting neonatologists especially in developing countries. This study was undertaken to investigate whether PICCs is a safe treatment for very low birth weight (VLBW) infants and extremely low birth weight (ELBW) infants. Methods: Fifty-nine VLBW and ELBW infants receiving PICCs and 89 VLBW and ELBW infants receiving peripheral intravenous catheters (PIVCs) were included in this study. The incidence of sepsis and mortality were compared retrospectively between the two groups. Results: There was no difference in the total sepsis incidence and mortality between the PICCs and PIVCs groups (P=0.11 and P=0.61 respectively). However, the candidal sepsis incidence was higher in the PICCs group than in the PIVCs group [6/59 (10.2%) vs 2/89 (2.2%); P=0.044 (Exat Sig. 1-sided), OR=4.93, 95% CI 0.96-25.3]. Conclusion: Placement and indwelling of PICCs are a potential risk factor for candidal sepsis among VLBW and ELBW infants.
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