期刊
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
卷 30, 期 3, 页码 1135-1139出版社
SPRINGER
DOI: 10.1007/s11274-013-1531-x
关键词
Marine gliding bacterium; Rapidithrix thailandica; Amino phenyl pyrrolidone derivative; Antibacterial activities; Vancomycin-resistant Enterococcus faecalis (VRE)
资金
- Prince of Songkla University
A recently described marine gliding bacterium Rapidithrix thailandica strain TISTR 1741 was isolated from biofilm specimen collected from the Andaman Sea in Thailand. Four liters fermentation broth of R. thailandica TISTR 1741 cultivated in VY/2 medium were extracted with methanol to yield a novel amino phenyl pyrrolidone derivative compound (1) with antibacterial activities. The chemical structure and physico-chemical properties of 1 were investigated by spectrometry techniques. Compound 1 exhibited selective inhibition against vancomycin-resistant Enterococcus faecalis (VRE) with the MIC of 5.97 mM.
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