期刊
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
卷 26, 期 10, 页码 1735-1743出版社
SPRINGER
DOI: 10.1007/s11274-010-0352-4
关键词
Prebiotic activity; Blackcurrant products; Modulation of gut microbiota; Rats
资金
- Four Leaf Japan Co., Ltd.
- Just the Berries Ltd
An animal model was used to assess the effects of orally administered aqueous extract from two commercial health supplement ingredients; First Leaf (FL; composed of blackcurrant extract powder, lactoferrin and lutein and is developed by the Four Leaf Japan Co. Ltd, Japan) and Cassis Anthomix 30 (CAM30; blackcurrant extract powder which is developed by Just the Berries Ltd, New Zealand) on the proliferation of lactobacilli and bifidobacterial species and some undesirable bacteria in the caeca of rats. Gavaging rats with CAM30, FL or inulin three times weekly for 4 weeks resulted in a significant increase in the numbers of bifidobacteria and/or lactobacilli and a significant decrease in the numbers of bacteroides and clostridia. Moreover, rats gavaged with FL, CAM30 and inulin showed 31.5, 18 and 15% reduction in the activity of beta-glucuronidase and 26, 30.4 and 18% increment in the activity of beta-glucosidase when compared to the control group gavaged with water, respectively. These benefits may make these products good candidates as prebiotic agents. In conclusion, this study has shown that FL and CAM30 can positively modulate key markers of gastrointestinal function in rats.
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