期刊
WORLD JOURNAL OF GASTROENTEROLOGY
卷 20, 期 18, 页码 5320-5330出版社
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.3748/wjg.v20.i18.5320
关键词
Nonalcoholic fatty liver disease; Nonalcoholic steatohepatitis; Liver cirrhosis; Liver transplantation; Metabolic syndrome
Nonalcoholic fatty liver disease (NAFLD) is becoming rapidly one of the most common indications for orthotopic liver transplantation in the world. Development of graft steatosis is a significant problem during the posttransplant course, which may happen as a recurrence of pre-existing disease or de novo NAFLD. There are different risk factors that might play a role in development of graft steatosis including post-transplant metabolic syndrome, immune-suppressive medications, genetics and others. There are few studies that assessed the effects of NAFLD on graft and patient survival; most of them were limited by the duration of follow up or by the number of patients. With this review article we will try to shed light on post-liver transplantation NAFLD, significance of the disease, how it develops, risk factors, clinical course and treatment options. (C) 2014 Baishideng Publishing Group Co., Limited. All rights reserved.
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