期刊
WORLD JOURNAL OF GASTROENTEROLOGY
卷 16, 期 42, 页码 5272-5279出版社
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.3748/wjg.v16.i42.5272
关键词
Intestinal damage; Markers; Human; Gut wall integrity
The intestinal mucosa is responsible for the absorption of nutrients from the lumen and for the separation of the potentially toxic lumina] content (external environment) from the host (internal environment). Disruption of this delicate balance at the mucosal interface is the basis for numerous (intestinal) diseases. Experimental animal studies have shown that gut wall integrity loss is involved in the development of various inflammatory syndromes, including post-operative or post-traumatic systemic inflammatory response syndrome, sepsis, and multiple organ failure. Assessment of gut wall integrity in clinical practice is still a challenge, as it is difficult to evaluate the condition of the gut non-invasively with currently available diagnostic tools. Moreover, non-invasive, rapid diagnostic means to assess intestinal condition are needed to evaluate the effects of treatment of intestinal disorders. This review provides a survey of non-invasive tests and newly identified markers that can be used to assess gut wall integrity. (C) 2010 Baishideng. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据