期刊
WORLD JOURNAL OF GASTROENTEROLOGY
卷 15, 期 3, 页码 270-279出版社
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.3748/wjg.15.270
关键词
Inflammatory bowel disease; Crohn's disease; Ulcerative colitis; Etiology; Risk factors; Protective factors; NOD2/CARD15; Single nucleotide polymorphisms
Inflammatory bowel disease is a chronic, debilitating disorder of the gastrointestinal tract. The etiology of inflammatory bowel disease has not been elucidated, but is thought to be multifactorial with both environmental and genetic influences. A large body of research has been conducted to elucidate the etiology of inflammatory bowel disease. This article reviews this literature, emphasizing the studies of breastfeeding and the studies of genetic factors, particularly NOD2 polymorphisms. (C) 2009 The WJG Press and Baishideng. All rights reserved.
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