期刊
WORLD JOURNAL OF GASTROENTEROLOGY
卷 15, 期 22, 页码 2701-2707出版社
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.3748/wjg.15.2701
关键词
Helicobacter pylori; Hormones; Thyroid; Osteoporosis; Diabetes; Dyslipidemia
Helicobacter pylori (H pylori) infection is a leading world-wide infectious disease as it affects more than half of the world population and causes chronic gastritis, peptic ulcer disease and gastric malignancies. The infection elicits a chronic cellular inflammatory response in the gastric mucosa. However, the effects of this local inflammation may not be confined solely to the digestive tract but may spread to involve extra-intestinal tissues and/or organs. Indeed, H pylori infection has been epidemiologically linked to extra-digestive conditions and diseases. In this context, it has been speculated that H pylori infection may be responsible for various endocrine disorders, such as autoimmune thyroid diseases, diabetes mellitus, dyslipidemia, obesity, osteoporosis and primary hyperparathyroidism. This is a review of the relationship between H pylori infection and these endocrine disorders. (C) 2009 The WJG Press and Baishideng. All rights reserved.
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