期刊
WORLD JOURNAL OF GASTROENTEROLOGY
卷 15, 期 45, 页码 5633-5640出版社
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.3748/wjg.15.5633
关键词
MicroRNA; Hepatitis; Fatty liver; Fibrosis; Cirrhosis
资金
- NIAAA NIH HHS [R01 AA011576, AA011576-10A1] Funding Source: Medline
MicroRNAs are a class of small non-coding RNAs that are found in plants, animals, and some viruses. They modulate the gene function at the post-transcriptional level and act as a fine tuner of various processes, such as development, proliferation, cell signaling, and apoptosis. They are associated with different types and stages of cancer. Recent studies have shown the involvement of microRNAs in liver diseases caused by various factors, such as Hepatitis C, Hepatitis B, metabolic disorders, and by drug abuse. This review highlights the role of microRNAs in liver diseases and their potential use as therapeutic molecules. (C) 2009 The WJG Press and Baishideng. All rights reserved.
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