期刊
WORLD JOURNAL OF GASTROENTEROLOGY
卷 15, 期 38, 页码 4770-4774出版社
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.3748/wjg.15.4770
关键词
Hepatic steatosis; Nonalcoholic fatty liver disease; Metabolic syndrome; Carotid atherosclerosis; Plaque; Intima-media thickness
资金
- Gruppo Italiano di Ultrasonologia in Medicina Intema (GIUMI)
AIM: To ascertain whether carotid lesions are more prevalent in outpatients with incidental findings of nonalcoholic fatty liver disease (NAFLD) at abdominal ultrasound (US). METHODS: One hundred and fifty-four consecutive outpatients (age range 24-90 years, both sexes) referred by general practitioners for abdominal US, and drinking less than 20 g alcohol/day, underwent carotid US for an assessment of carotid intima-media thickness (c-IMT) and carotid plaque prevalence. Hepatic steatosis, visceral fat thickness and subcutaneous fat thickness were also assessed at ultrasonography. RESULTS: Higher c-IMT values were found in the presence of NAFLD (90 patients), even after adjustment for indices of general and abdominal obesity and for the principal cardiovascular risk factors (0.84 +/- 0.10 mm vs 0.71 +/- 0.10 mm, P < 0.001). The prevalence of carotid plaques was 57.8% in the patients with NAFLD vs 37.5% in the patients without this condition (P = 0.02). The adjusted relative risk of having carotid plaques for patients with NAFLD was 1.85 (95% CI: 1.33-2.57, P < 0.001). CONCLUSION: An incidental finding of hepatic steatosis may suggest the presence of silent carotid atherosclerotic lesions. (C) 2009 The WJG Press and Baishideng. All rights reserved.
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