期刊
WORLD JOURNAL OF GASTROENTEROLOGY
卷 14, 期 27, 页码 4300-4308出版社
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.3748/wjg.14.4300
关键词
hepatocellular carcinoma; epidemiology; risk factors; aetiology; pathogenesis
资金
- Medical Research Council Funding Source: Medline
Hepatocellular carcinoma (HCC) is the commonest primary malignant cancer of the liver in the world. Given that the burden of chronic liver disease is expected to rise owing to increasing rates of alcoholism, hepatitis B and C prevalence and obesity-related fatty liver disease, it is expected that the incidence of HCC will also increase in the foreseeable future. This article summarizes the international epidemiology, the risk factors and the pathogenesis of HCC, including the roles of viral hepatitis, toxins, such as alcohol and aflatoxin, and insulin resistance. (c) 2008 The WJG Press. All rights reserved.
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