4.2 Article

Repeated intrauterine IgG infusions in foetal alloimmune thrombocytopenia do not increase foetal platelet counts

期刊

VOX SANGUINIS
卷 99, 期 4, 页码 348-353

出版社

WILEY
DOI: 10.1111/j.1423-0410.2010.01367.x

关键词

foetal alloimmune thrombocytopenia; foetal IgG infusion; intrauterine therapy

向作者/读者索取更多资源

Background and Objectives Foetal alloimmune thrombocytopenia (FNAIT) is often treated transplacentally with maternally administered i.v. immunoglobulins, but not all foetuses show a consistent platelet increase during such treatment. Materials and Methods We retrospectively analysed data from a cohort of ten foetuses with FNAIT treated by direct foetal immunoglobulin infusion. Foetal treatment was begun between 17 and 25 weeks and continued until 36 weeks with weekly cordocenteses and foetal immunoglobulin infusions. Results While foetal IgG levels increased steadily during weekly IgG infusions, foetal platelet counts remained unchanged. Conclusion Our retrospective study presents a unique analysis of a historical cohort, contributing to the ongoing debate about the treatment of choice for foetal alloimmune thrombocytopenia.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.2
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据