期刊
VISION RESEARCH
卷 49, 期 1, 页码 115-126出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.visres.2008.09.029
关键词
Retinal ganglion cells; Visual streak; Fluorescent tracers; Computerized image analysis; Retina; Rat; Retrograde labelling
资金
- Regional Government of Murcia [CARM BIO2005/016469]
- Fundacion Seneca [02989/PI/05, 05703/PI/07, 04446/GERM/07]
- Spanish Ministry of Education and Science [SAF-2005-04812]
- Spanish Ministry of Health ISCIII [FIS PIO06/0780, RD07/0062/0001]
In adult albino (SD) and pigmented (PVG) rats the entire population of retinal ganglion cells (RGCs) was quantified and their spatial distribution analyzed using a computerized technique. RGCs were back-labelled from the optic nerves (ON) or the superior colliculi (SCi) with Fluorogold (FG). Numbers of RGCs labelled from the ON [SD: 82,818 +/- 3,949, n = 27; PVG: 89,241 +/- 3,576, n = 6) were comparable to those labelled from the SCi [SD: 81,486 +/- 4,340, n = 37; PVC: 87,229 +/- 3,199; n = 59]. Detailed methodology to provide cell density information at small scales demonstrated the presence of a horizontal region in the dorsal retina with highest densities, resembling a visual streak. (C) 2008 Elsevier Ltd. All rights reserved.
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