期刊
VISION RESEARCH
卷 48, 期 14, 页码 1554-1561出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.visres.2008.04.013
关键词
myopia; refractive error; acuity; multifocal electroretinogram; optical coherence tomography
资金
- Public Health Agency [EAT/2532/03] Funding Source: researchfish
We investigated relationships between retinal structure using optical coherence tomography (OCT) and retinal function using peripheral resolution acuity and multifocal electroretinograms (mfERG) in 56 subjects with a range of refractive errors (+0.50 to -15.00 D). Retinal thinning occurred in moderate and high myopia which appeared to be primarily due to reduced thickness of the middle to inner retina (MIR) (outer plexiform layer to the nerve fiber layer). MIR thickness was Correlated with reduced spatial resolution and delayed mfERG timing in the peripheral retina. The findings suggest the structure and function of the post-receptor retina is susceptible to disruption in moderately and highly myopic eyes. (c) 2008 Elsevier Ltd. All rights reserved.
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