期刊
VIRUS RESEARCH
卷 178, 期 2, 页码 543-546出版社
ELSEVIER
DOI: 10.1016/j.virusres.2013.09.017
关键词
Severe fever with thrombocytopenia; syndrome virus; Reassortment
类别
资金
- Projects of Shandong Province Higher Educational Science and Technology Program [J12LE06]
Recently, a novel bunyavirus, severe fever with thrombocytopenia syndrome virus (SFTSV), was isolated in central China. The virus can cause multi-clinical symptoms: severe fever, thrombocytopenia, leukocy-topenia, with a mortality rate of similar to 10%. Several studies show that SFTSV could undergo rapid evolution via gene mutation and homologous recombination. However, as an important evolutionary force for segmented-genome viruses, reassortment has not been reported in SFTSV. In this study, we identified two SFTSV strains of which the S segment has different origin from M and L, suggesting that reassortment might be potential force driving rapid change of SFTSV. This result might shed new light on the evolutionary behavior of the novel virus. (C) 2013 Elsevier B.V. All rights reserved.
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