期刊
VIRUS RESEARCH
卷 151, 期 2, 页码 205-212出版社
ELSEVIER
DOI: 10.1016/j.virusres.2010.05.008
关键词
Hantavirus; Protein interaction; Zinc finger
类别
资金
- Academy of Finland
- Sigrid Juselius Foundation, Finland
- Graduate School on Biotechnology and Molecular Biology
- Helsinki Biomedicum Graduate School
Hantaviral N and Gn proteins were shown to interact, thus providing the long-awaited evidence for one of the crucial steps in the virus replication at which RNPs are directed to the site of the virus assembly. Using pull-down assay and point mutagenesis it was demonstrated that intact, properly folded zinc fingers in the Gn protein cytoplasmic tail as well as the middle domain of the N protein (that includes aa residues 80-248) are essential for the interaction. (C) 2010 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据